Immunity to schistosomes: progress toward vaccine

A Capron, JP Dessaint, M Capron, JH Ouma… - Science, 1987 - science.org
Among the major parasitic infections, schistosomiasis may be the most promising candidate
for human vaccination. Information about mechanisms of immunity, gained mainly from …

Immunity and morbidity in schistosomiasis japonicum infection.

GR Olds, R Olveda, G Wu, P Wiest… - The American journal …, 1996 - europepmc.org
Schistosomiasis japonica differs significantly from Schistosoma mansoni infection in several
epidemiologic, immunologic, and operational characteristics for control. Because of …

Cytokine production in acute versus chronic human schistosomiasis mansoni: the cross-regulatory role of interferon-γ and interleukin-10 in the responses of peripheral …

SML Montenegro, P Miranda, S Mahanty… - The Journal of …, 1999 - academic.oup.com
The contribution of interleukin (IL)-10 and interferon (IFN)-γ to the regulation of type 1 and
type 2 cytokine responses was investigated in Brazilians with different clinical forms of …

Immunopathology of granuloma formation and fibrosis in schistosomiasis

SM Phillips, PJ Lammie - Parasitology today, 1986 - Elsevier
In schistosomiasis the deposition of parasite ova within host tissues is the initial event in a
complex pathophysiological cascade which is characterized by granuloma formation, and …

The pathogenesis of granulomatous inflammation and organ injury in schistosomiasis: interactions between the schistosome ova and the host

JV Weinstock - Immunological investigations, 1992 - Taylor & Francis
Schistosomiasis results from infection with parasites called schistosomes that inhabit
specific blood vessels of their definitive host. Schistosomiasis is predominantly a disease of …

The role of T-cell anergy in the immunomodulation of schistosomiasis

MJ Stadecker - Parasitology Today, 1992 - cell.com
Schistosomes are capable of causing severe tissue damage, which results from the
granulomatous inflammation that develops around the parasite eggs. Characteristic of this …

Immune responses during human schistosomiasis mansoni. XVI. Idiotypic differences in antibody preparations from patients with different clinical forms of infection.

MA Montesano, MS Lima, R Correa-Oliveira… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
Antibodies were purified from pooled sera from patients with different clinical forms of
schistosomiasis mansoni on immunoaffinity columns of schistosome soluble egg Ag (SEA) …

Neonatal exposure to idiotype induces Schistosoma mansoni egg antigen-specific cellular and humoral immune responses

MA Montesano, DG Colley, GL Freeman… - The Journal of …, 1999 - journals.aai.org
Exposure of neonatal mice to appropriate, cross-reactive Id (CRI) preparations alters
immune responsiveness, ameliorates pathology, and prolongs survival of animals upon …

Immune responses during human Schistosomiasis mansoni. Evidence for antiidiotypic T lymphocyte responsiveness.

MS Lima, G Gazzinelli, E Nascimento… - The Journal of …, 1986 - Am Soc Clin Investig
We present a method for the examination of antiidiotypic cell-mediated reactivity during
chronic human infections. Pooled and individual sera from patients with schistosomiasis …

Parasite antigens are present in breast milk of women infected with Onchocerca volvulus.

I Petralanda, L Yarzabal… - The American journal of …, 1988 - europepmc.org
We used a noncompetitive two-site ELISA with 5 monoclonal antibodies to determine
whether parasite antigens are present in breast milk from women infected with Onchocerca …