Blood-brain barrier, blood-brain tumor barrier, and fluorescence-guided neurosurgical oncology: delivering optical labels to brain tumors

E Belykh, KV Shaffer, C Lin, VA Byvaltsev… - Frontiers in …, 2020 - frontiersin.org
Recent advances in maximum safe glioma resection have included the introduction of a host
of visualization techniques to complement intraoperative white-light imaging of tumors …

Nanotechnology meets glioblastoma multiforme: Emerging therapeutic strategies

D Liu, X Dai, L Ye, H Wang, H Qian… - Wiley …, 2023 - Wiley Online Library
Glioblastoma multiforme (GBM) represents the most common and fatal form of primary
invasive brain tumors as it affects a great number of patients each year and has a median …

Nanotechnology and nanocarrier-based drug delivery as the potential therapeutic strategy for glioblastoma multiforme: An update

JF Hsu, SM Chu, CC Liao, CJ Wang, YS Wang, MY Lai… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) are among the most lethal tumors. The
highly invasive nature and presence of GBM stem cells, as well as the blood brain barrier …

Recurrent glioblastoma: a review of the treatment options

MA Vaz-Salgado, M Villamayor, V Albarrán, V Alía… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is the most common malignant brain tumor associated with a
poor prognosis, with a median survival of 14 months. Despite initial treatment with surgery …

Surgical management of Glioma Grade 4: technical update from the neuro-oncology section of the Italian Society of Neurosurgery (SINch®): a systematic review

T Ius, G Sabatino, PP Panciani, MM Fontanella… - Journal of neuro …, 2023 - Springer
Purpose The extent of resection (EOR) is an independent prognostic factor for overall
survival (OS) in adult patients with Glioma Grade 4 (GG4). The aim of the neuro-oncology …

Surgical treatment of glioblastoma: State-of-the-art and future trends

AHA Sales, J Beck, O Schnell, C Fung, B Meyer… - Journal of Clinical …, 2022 - mdpi.com
Glioblastoma (GBM) is a highly aggressive disease and is associated with poor prognosis
despite treatment advances in recent years. Surgical resection of tumor remains the main …

Label-free macroscopic fluorescence lifetime imaging of brain tumors

M Lukina, K Yashin, EE Kiseleva, A Alekseeva… - Frontiers in …, 2021 - frontiersin.org
Advanced stage glioma is the most aggressive form of malignant brain tumors with a short
survival time. Real-time pathology assisted, or image guided surgical procedures that …

Treatment of recurrent glioblastoma: state-of-the-art and future perspectives

V Di Nunno, E Franceschi, A Tosoni… - Expert review of …, 2020 - Taylor & Francis
Background Almost all patients affected by glioblastoma experience recurrence of the
disease. Areas covered Management of recurrent glioblastoma is a clinical challenge, and …

Effect of Extent of Resection on Survival of Patients with Glioblastoma, IDH–Wild-Type, WHO Grade 4 (WHO 2021): Systematic Review and Meta-Analysis

I Jusue-Torres, J Lee, AV Germanwala, TC Burns… - World neurosurgery, 2023 - Elsevier
Background In light of the recently updated World Health Organization (WHO) 2021 central
nervous system tumor classifications, the aim of the present study was to establish the effect …

Alpha 1-antichymotrypsin contributes to stem cell characteristics and enhances tumorigenicity of glioblastoma

M Lara-Velazquez, N Zarco, A Carrano… - Neuro …, 2021 - academic.oup.com
Abstract Background Glioblastomas (GBMs) are the main primary brain tumors in adults with
almost 100% recurrence rate. Patients with lateral ventricle proximal GBMs (LV-GBMs) …