Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

Heme oxygenase (HO)-1 is known to metabolize heme into biliverdin/bilirubin, carbon
monoxide, and ferrous iron, and it has been suggested to demonstrate cytoprotective effects …

Ferroptosis is a form of oxidative cell death and has become a chemotherapeutic target for
cancer treatment. BAY 11–7085 (BAY), which is a well-known IκBα inhibitor, suppressed …

Ferroptosis is a form of oxidative cell death and has become a chemotherapeutic target for
cancer treatment. Curcumin (CUR), a well‐known cancer inhibitor, significantly inhibits the …

Atherosclerosis is an inflammatory process of the vascular wall characterized by the
infiltration of lipids and inflammatory cells. Oxidative modifications of infiltrating low-density …

Free radicals and other so-called 'reactive species' are constantly produced in the brain in
vivo. Some arise by 'accidents of chemistry', an example of which may be the leakage of …

In my career I have moved from chemistry to biochemistry to plant science to clinical
chemistry and back again (in a partial way) to plants. This review presents a brief history of …

Object. The mechanisms involved in brain edema formation following intracerebral
hemorrhage (ICH) have not been fully elucidated. The authors have found that red blood cell …

Ferroptosis is a novel type of regulated cell death which is driven by iron-dependent lipid
peroxidation and subsequent plasma membrane ruptures. Since ferroptosis was coined …

Intracerebral hemorrhage (ICH) is a common and often fatal subtype of stroke that produces
severe neurologic deficits in survivors. Although death may occur acutely after an ICH …