Glioblastoma (GBM) is one of the most aggressive brain tumors and has a high recurrence
rate, and effective treatment is urgently needed. GBM stem cells (GSCs) contribute to GBM …

Nonhuman primates are essential for the study of human disease and to explore the safety
of new diagnostics and therapies proposed for human use. They share similar genetic …

Zika virus (ZIKV) strains are classified into the African and Asian genotypes. The higher
virulence of the African MR766 strain, which has been used extensively in ZIKV research, in …

Concerns have arisen that pre-existing immunity to dengue virus (DENV) could enhance
Zika virus (ZIKV) disease, due to the homology between ZIKV and DENV and the …

Introduction Zika virus (ZIKV) infection during pregnancy results in a spectrum of birth
defects and neurodevelopmental deficits in prenatally exposed infants, with no clear …

Countermeasures against Zika virus (ZIKV), including vaccines, are frequently tested in
nonhuman primates (NHP). Macaque models are important for understanding how ZIKV …

Mosquito-borne dengue (DENV) and Zika (ZIKV) viruses originated in Old World sylvatic
(forest) cycles involving monkeys and canopy-living Aedes mosquitoes. Both viruses spilled …

Bone-related diseases (osteopathologies) associated with human virus infections have
increased around the globe. Recent findings have highlighted the intricate interplay …

In the 2016 Zika virus (ZIKV) pandemic, a previously unrecognized risk of birth defects
surfaced in babies whose mothers were infected with Asian-lineage ZIKV during pregnancy …

Zika virus (ZIKV) was identified as a teratogen in 2016 when an increase in severe
microcephaly and other brain defects was observed in fetuses and newborns following …