Direct Functionalization of para‐Quinones: A Historical Review and New Perspectives

R Kumar Jha, S Kumar - European Journal of Organic …, 2024 - Wiley Online Library
The direct functionalization of quinones has always fascinated research communities due to
their biological and redox activities and subsequent application. Quinone motifs play a vital …

Recent advances in direct functionalization of quinones

Y Wang, S Zhu, LH Zou - European Journal of Organic …, 2019 - Wiley Online Library
Developing methods for the direct functionalization of quinones for assembly of highly
functionalized quinones or bioactive natural products is an essential topic in the field of …

C− H functionalization of 1, 4-naphthoquinone by oxidative coupling with anilines in the presence of a catalytic quantity of copper (II) acetate

CS Lisboa, VG Santos, BG Vaz… - The Journal of …, 2011 - ACS Publications
The oxidative addition of anilines (2) with 1, 4-naphthoquinone (3) to give N-aryl-2-amino-1,
4-naphthoquinones (1) was found to be catalyzed by copper (II) acetate. In the absence of …

[图书][B] Progress in heterocyclic chemistry

G Gribble, J Joule - 2009 - books.google.com
Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the
International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both …

Synthesis, antitumor activity and docking of 2, 3-(substituted)-1, 4-naphthoquinone derivatives containing nitrogen, oxygen and sulfur

M Delarmelina, RD Daltoé, MF Cerri… - Journal of the Brazilian …, 2015 - SciELO Brasil
Eleven 2, 3-(substituted)-1, 4-naphthoquinone derivatives were synthesized in yields
ranging from 52-89%. These derivatives were evaluated for their cytotoxic effects on human …

Pd-catalyzed threefold arylations of mono, di and tetra-bromoquinones using triarylbismuth reagents

MLN Rao, S Giri - RSC advances, 2012 - pubs.rsc.org
The palladium-catalyzed efficient cross-couplings of mono-, di-and tetra-bromo-1, 4-
quinones with triarylbismuth reagents were developed, involving threefold arylation. This …

Highly Selective 1,4‐ and 1,6‐Addition of P(O)H Compounds to p‐Quinones: A Divergent Method for the Synthesis of C‐ and O‐Phosphoryl Hydroquinone …

B Xiong, R Shen, M Goto, SF Yin… - Chemistry–A European …, 2012 - Wiley Online Library
The reaction of P (O) H compounds with p‐quinones could proceed through either 1, 4‐or
1, 6‐addition pathways by employing different additives to selectively give the …

Synthesis, biological evaluation, and molecular docking studies of 2, 5-substituted-1, 4-benzoquinone as novel urease inhibitors

ZL You, DM Xian, M Zhang, XS Cheng, XF Li - Bioorganic & medicinal …, 2012 - Elsevier
A series of 2, 5-substituted-1, 4-benzoquinone (1–6) were prepared and structurally
characterized by elemental analysis, IR spectra, 1H and 13C NMR spectra, and single …

Synthetic enamine naphthoquinone derived from lawsone as cytotoxic agents assessed by in vitro and in silico evaluations

BC Lemos, R Westphal, E Venturini Filho… - Bioorganic & Medicinal …, 2021 - Elsevier
We synthesized ten enamine naphthoquinones with yields ranging from 43 to 76%. These
compounds were screened for their in vitro antiproliferative activities by MTT assay against …

Laccase-induced derivatization of unprotected amino acid L-tryptophan by coupling with p-hydroquinone 2,5-dihydroxy-N-(2-hydroxyethyl)-benzamide

K Manda, E Hammer, A Mikolasch, D Gördes… - Amino Acids, 2006 - Springer
We have studied the enzymatic derivatization of amino acids by use of the polyphenol
oxidase laccase. Derivatization of L-tryptophan was achieved by enzymatic crosslinking with …