Cellular infiltration in traumatic brain injury

A Alam, EP Thelin, T Tajsic, DZ Khan, A Khellaf… - Journal of …, 2020 - Springer
Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …

The far-reaching scope of neuroinflammation after traumatic brain injury

DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

Traumatic brain injuries

K Blennow, DL Brody, PM Kochanek, H Levin… - Nature reviews Disease …, 2016 - nature.com
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …

Fluid biomarkers for mild traumatic brain injury and related conditions

H Zetterberg, K Blennow - Nature reviews neurology, 2016 - nature.com
Diagnostic and prognostic biomarkers for mild traumatic brain injury (TBI), also known as
concussion, remain a major unmet clinical need. Moderate to severe TBI can be diagnosed …

Emerging roles for the immune system in traumatic brain injury

CA McKee, JR Lukens - Frontiers in immunology, 2016 - frontiersin.org
Traumatic brain injury (TBI) affects an ever-growing population of all ages with long-term
consequences on health and cognition. Many of the issues that TBI patients face are thought …

Priming the inflammatory pump of the CNS after traumatic brain injury

KG Witcher, DS Eiferman, JP Godbout - Trends in neurosciences, 2015 - cell.com
Traumatic brain injury (TBI) can lead to secondary neuropsychiatric problems that develop
and persist years after injury. Mounting evidence indicates that neuroinflammatory …

Wireless charging-mediated angiogenesis and nerve repair by adaptable microporous hydrogels from conductive building blocks

RS Hsu, SJ Li, JH Fang, IC Lee, LA Chu, YC Lo… - Nature …, 2022 - nature.com
Traumatic brain injury causes inflammation and glial scarring that impede brain tissue
repair, so stimulating angiogenesis and recovery of brain function remain challenging. Here …

The immunological response to traumatic brain injury

EJ Needham, A Helmy, ER Zanier, JL Jones… - Journal of …, 2019 - Elsevier
Traumatic brain injury (TBI) is the leading cause of death and disability in young adults in the
developed world. The accuracy of early outcome-prediction remains poor even when all …

Dissemination of brain inflammation in traumatic brain injury

K Shi, J Zhang, J Dong, FD Shi - Cellular & molecular immunology, 2019 - nature.com
Traumatic brain injury (TBI) is recognized as a global health problem due to its increasing
occurrence, challenging treatment, and persistent impacts on brain pathophysiology. Neural …

The inflammatory continuum of traumatic brain injury and Alzheimer's disease

ON Kokiko-Cochran, JP Godbout - Frontiers in immunology, 2018 - frontiersin.org
The post-injury inflammatory response is a key mediator in long-term recovery from
traumatic brain injury (TBI). Moreover, the immune response to TBI, mediated by microglia …