Preeclampsia: maternal systemic vascular disorder caused by generalized endothelial dysfunction due to placental antiangiogenic factors

T Tomimatsu, K Mimura, S Matsuzaki, M Endo… - International journal of …, 2019 - mdpi.com
Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …

Viral infections during pregnancy

M Silasi, I Cardenas, JY Kwon, K Racicot… - American journal of …, 2015 - Wiley Online Library
Viral infections during pregnancy have long been considered benign conditions with a few
notable exceptions, such as herpes virus. The recent Ebola outbreak and other viral …

Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease

CE Powe, RJ Levine, SA Karumanchi - Circulation, 2011 - Am Heart Assoc
Preeclampsia is a clinical syndrome defined as the new onset of hypertension and
proteinuria during the second half of pregnancy. 1 It afflicts 3% to 5% of pregnancies and is …

Sex differences in cardiovascular disease–impact on care and outcomes

KH Humphries, M Izadnegahdar, T Sedlak… - Frontiers in …, 2017 - Elsevier
Globally, cardiovascular disease (CVD) is the number one killer of women; one third of
female deaths are due to ischemic heart disease and stroke (WHO, 2013). Historically …

Pre-eclampsia and future cardiovascular risk among women: a review

R Ahmed, J Dunford, R Mehran, S Robson… - Journal of the American …, 2014 - jacc.org
Cardiovascular disease continues to be the leading cause of death in the western world.
Due to advancements in diagnosis, prevention, and treatment, cardiovascular mortality has …

Endothelial function

JA Vita - Circulation, 2011 - Am Heart Assoc
The endothelium regulates vascular tone, platelet activity, leukocyte adhesion, and
angiogenesis by producing nitric oxide and other regulatory factors. Risk factors decrease …

Pre-eclampsia and cardiovascular disease

CW Chen, IZ Jaffe, SA Karumanchi - Cardiovascular research, 2014 - academic.oup.com
Heart disease is the leading cause of death in women in all countries. A history of pre-
eclampsia, one of the most deadly hypertensive complications of pregnancy, increases …

Androgens and the masculinization programming window: human–rodent differences

RM Sharpe - Biochemical Society Transactions, 2020 - portlandpress.com
Human male reproductive disorders are common and may have a fetal origin—the testicular
dysgenesis syndrome (TDS) hypothesis. In rats, experimentally induced TDS disorders …

Endothelial function and circulating biomarkers are disturbed in women and children after preeclampsia

AS Kvehaugen, R Dechend, HB Ramstad, R Troisi… - …, 2011 - Am Heart Assoc
Preeclampsia is a long-term cardiovascular risk factor for the mother and possibly the
offspring. Preeclampsia and cardiovascular diseases share common pathophysiological …

Endothelial dysfunction in ME/CFS patients

MK Sandvik, K Sørland, E Leirgul, IG Rekeland… - PLoS …, 2023 - journals.plos.org
Objective A few earlier studies have found impaired endothelial function in patients with
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The present study …