The influx and efflux of cells and antigens to and from the draining lymph nodes largely take
place through the subcapsular, cortical and medullary sinus systems. Recent analyses in …

Tumor cells metastasize to distant organs through a complex series of events that are driven
by tumor intrinsic and extrinsic factors. In particular, non-malignant stromal cells, including …

Review on mannose receptor as an endocytic receptor in antigen delivery that is co-
expressed with the microRNA miR-511-3p encoded within the Mrc1 gene. The MR is a …

Lymphatic vessels collect interstitial fluid that has extravasated from blood vessels and
return it to the circulatory system. Another important function of the lymphatic network is to …

Hematological malignancies possess a distinctive immunologic microenvironment
compared with solid tumors. Here, using an established computational algorithm …

The trafficking of leukocytes into and within lymphoid and peripheral tissues is central to
immune cell development, immunosurveillance and effector function. Interstitial leukocyte …

Tumor-associated macrophages (TAM) are an important component of the tumor stroma and
exert several tumor-promoting activities. Strongly pro-angiogenic TAMs that reside in …

The liver sinusoidal endothelial cell (LSEC) forms the fenestrated wall of the hepatic
sinusoid and functions as a control post regulating and surveying the trafficking of molecules …

T cell migration within and between peripheral tissues and secondary lymphoid organs is
essential for proper functioning of adaptive immunity. While active T cell migration within a …

Until recently, the known roles of lymphatic endothelial cells (LECs) in immune modulation
were limited to directing immune cell trafficking and passively transporting peripheral Ags to …