Maintenance therapy (MT) with oral methotrexate (MTX) and 6-mercaptopurine (6-MP) is
essential for the cure of acute lymphoblastic leukemia (ALL). MTX and 6-MP interfere with …

Abstract The Children's Oncology Group (COG) Diversity and Health Disparities Committee's
(DHDC's) mission is to guarantee the highest standard of care for children and adolescents …

Opinion Statement Acute lymphoblastic leukemia (ALL) represents the predominant cancer
in pediatric populations, though its occurrence in adults is relatively rare. Pre-treatment risk …

Background: The relevance of the study lies in the fact that although the role of
polymorphism of some genes that are responsible for cell apoptosis and deoxyribonucleic …

Background Aim of this study is to estimate the burden of leukaemia in children and
adolescents, as well as the socio-demographic index (SDI), for 21 regions around the world …

This study delivers a comprehensive evaluation of the efficacy and pharmacokinetics of high‐
dose methotrexate (HDMTX) in a large cohort of Chinese paediatric acute lymphoblastic …

Abstract The St Jude Total Therapy Study XV was the first clinical trial to prospectively use
minimal residual disease levels during and after remission induction therapy to guide risk …

Objectives. This study aimed to find the association between clinical characteristics,
cytogenetics, and post-induction outcomes of childhood acute lymphoblastic leukemia …

背景: 血小板输注疗效影响临床诊疗效果及临床决策, 目前缺乏针对急性淋巴细胞白血病(ALL)
患儿的血小板输注后疗效的预测模型. 目的: 构建及验证ALL 患儿输注血小板后血小板校正计数 …

Background Symptom distress and functional impairments in children with leukemia directly
affect their quality of life. Objectives To identify subgroups of symptom distress and functional …