Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements
V Aggarwal, HS Tuli, F Thakral… - Experimental …, 2020 - journals.sagepub.com
Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-
spectrum applicability to prevent dreadful diseases such as cardiovascular disease …
spectrum applicability to prevent dreadful diseases such as cardiovascular disease …
Hesperidin protects liver and kidney against sodium fluoride-induced toxicity through anti-apoptotic and anti-autophagic mechanisms
Aim High dose of fluoride intake is associated with toxic effects on liver and kidney tissues.
One approach to tackle these toxicities is using natural antioxidants as supplements. This …
One approach to tackle these toxicities is using natural antioxidants as supplements. This …
Flavonoids as potential therapeutics in male reproductive disorders
R Mishra, A Nikam, J Hiwarkar, T Nandgude… - Future Journal of …, 2024 - Springer
Background Male infertility presents global challenges, as current drug-based treatments
demonstrate limited effectiveness due to an incomplete understanding of dysfunctions within …
demonstrate limited effectiveness due to an incomplete understanding of dysfunctions within …
Minocycline can reduce testicular apoptosis related to varicocele in male rats
M Shokoohi, A Khaki, A Roudi Rasht Abadi… - Andrologia, 2022 - Wiley Online Library
The current research aimed to assess the impacts of Minocycline on varicocele‐induced
regulation of apoptotic‐related genes and oxidative stress in the testis of adult Wistar rats …
regulation of apoptotic‐related genes and oxidative stress in the testis of adult Wistar rats …
Sperm parameters, DNA integrity, and protamine expression in patients with type II diabetes mellitus
M Imani, AR Talebi, F Fesahat… - Journal of Obstetrics …, 2021 - Taylor & Francis
Diabetes Mellitus (DM) is the most common endocrine disorder affecting many human
physiological systems and tissues, including the reproductive organs in men. The age of …
physiological systems and tissues, including the reproductive organs in men. The age of …
Hesperidin mitigates cyclophosphamide-induced testicular dysfunction via altering the hypothalamic pituitary gonadal axis and testicular steroidogenesis …
T Khamis, AA Hegazy, SSA El-Fatah, ER Abdelfattah… - Pharmaceuticals, 2023 - mdpi.com
Cyclophosphamide (CP) is a cytotoxic, cell cycle, non-specific, and antiproliferative drug.
This study aimed to address the toxic effects of CP on male fertility and the possible …
This study aimed to address the toxic effects of CP on male fertility and the possible …
Ellagic acid effects on testis, sex hormones, oxidative stress, and apoptosis in the relative sterility rat model following busulfan administration
Background Busulfan is an antineoplastic medication that is broadly utilized for cancer
treatment. It affects the testicular function and leads to sterility. The present study aimed to …
treatment. It affects the testicular function and leads to sterility. The present study aimed to …
The palliative and antioxidant effects of hesperidin against lead-acetate-induced testicular injury in male Wistar rats
R Abu-Khudir, HH Almutairi, SS Abd El-Rahman… - Biomedicines, 2023 - mdpi.com
Lead (Pb)-induced reprotoxicity is a detrimental consequence of Pb exposure, which results
in abnormal spermatogenesis, testicular degeneration, and pathogenic sperm changes. The …
in abnormal spermatogenesis, testicular degeneration, and pathogenic sperm changes. The …
Eugenol improves tissue damage and oxidative stress in adult female rats after ovarian torsion/detorsion
The current study was designed to investigate the effect of eugenol on histopathological
changes and oxidative stress caused by torsion/detorsion in the ovary of adult female rats. In …
changes and oxidative stress caused by torsion/detorsion in the ovary of adult female rats. In …
Taurine and hesperidin rescues carbon tetrachloride-triggered testicular and kidney damage in rats via modulating oxidative stress and inflammation
YM Abd-Elhakim, MH Ghoneim, LLM Ebraheim… - Life Sciences, 2020 - Elsevier
Aims: This study assessed the prophylactic or therapeutic effects of taurine (TR) and/or
hesperidin (HES) on carbon tetrachloride (CCl 4) induced acute kidney and testicular injury …
hesperidin (HES) on carbon tetrachloride (CCl 4) induced acute kidney and testicular injury …