Recent advances in understanding the role of eukaryotic translation initiator factor 4E
(eIF4E) in tumorigenesis and cancer progression have generated significant interest in …

Recent technological advancements have shown tremendous mechanistic
accomplishments in our understanding of the mechanism of messenger RNA translation in …

Thymoquinone (TQ) and diosgenin (DG), the active ingredients obtained from black cumin
(Nigella sativa) and fenugreek (Trigonella foenum graecum), respectively, exert potent …

Over the last few decades, nanoparticles have been studied in theranostic field with the
objective of exhibiting a long circulation time through the body coupled to major …

Aberrant translation of proteins that promote cell proliferation is an essential factor that
defines oncogenic processes and cancer. The process for ribosomal translation of proteins …

Melanoma is a type of skin cancer that originates in the pigment-producing cells of the body
known as melanocytes. Most genetic aberrations in melanoma result in hyperactivation of …

Objective The aim of this study is to investigate whether EIF4A1, EIF4E, and EIF4G1 can
serve as prognostic markers for patients with cervical cancer receiving preoperative …

Background: Topical chemotherapy of skin cancers is a promising strategy for reduction of
side effects and for improvement of patient compliance. The combination of the …

Squamous cell carcinomas (SCCs), arising from the skin, head and neck, lungs, esophagus,
and cervix, are collectively among the most common cancers and a frequent cause of cancer …

In multiple human cancers, the function of the eukaryotic translation initiation factor 4E
(eIF4E) is elevated and directly related to disease progression. Overexpression or …