Nanoparticles and innate immunity: new perspectives on host defence

D Boraschi, P Italiani, R Palomba, P Decuzzi… - Seminars in …, 2017 - Elsevier
The innate immune system provides the first line of defence against foreign microbes and
particulate materials. Engineered nanoparticles can interact with the immune system in …

Nanomaterials and their impact on the immune system

AA Aljabali, MA Obeid, RM Bashatwah… - International journal of …, 2023 - mdpi.com
Nanomaterials have been the focus of intensive development and research in the medical
and industrial sectors over the past several decades. Some studies have found that these …

Vaccine technologies: From whole organisms to rationally designed protein assemblies

CP Karch, P Burkhard - Biochemical pharmacology, 2016 - Elsevier
Vaccines have been the single most significant advancement in public health, preventing
morbidity and mortality in millions of people annually. Vaccine development has traditionally …

[HTML][HTML] Elimination of p19ARF-expressing cells enhances pulmonary function in mice

M Hashimoto, A Asai, H Kawagishi, R Mikawa… - JCI insight, 2016 - ncbi.nlm.nih.gov
Senescent cells accumulate in many tissues as animals age and are considered to underlie
several aging-associated pathologies. The tumor suppressors p19 ARF and p16 INK4a …

Mechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP)

G Vietti, D Lison, S van den Brule - Particle and fibre toxicology, 2015 - Springer
Several experimental studies have shown that carbon nanotubes (CNT) can induce
respiratory effects, including lung fibrosis. The cellular and molecular events through which …

Harnessing nanotechnology for cardiovascular disease applications-a comprehensive review based on bibliometric analysis

Z Zheng, S Zhu, M Lv, Z Gu, H Hu - Nano Today, 2022 - Elsevier
Cardiovascular diseases (CVDs) remain the leading cause of health problems worldwide.
Nanotechnology, based on its unique properties, provides novel solutions to the diagnosis …

[HTML][HTML] Nanoestruturas de carbono (nanotubos, grafeno): Quo Vadis?

AJG Zarbin, MM Oliveira - Química Nova, 2013 - SciELO Brasil
We describe general considerations about the present and the future standing of carbon
nanostructures, mainly carbon nanotubes and graphene. Basic concepts and definitions …

The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro-and nanoparticles

V Rabolli, AA Badissi, R Devosse… - Particle and fibre …, 2014 - Springer
Background Inflammasome-activated IL-1β plays a major role in lung neutrophilic
inflammation induced by inhaled silica. However, the exact mechanisms that contribute to …

Mechanisms of carbon nanotube-induced toxicity: focus on pulmonary inflammation

K Bhattacharya, FT Andón, R El-Sayed… - Advanced drug delivery …, 2013 - Elsevier
Carbon nanotubes have gained tremendous interest in a wide range of applications due to
their unique physical, chemical, and electronic properties. Needless to say, close attention to …

Nanoparticle interaction with the immune system/Interakcije nanodelcev z imunskim sistemom

V Kononenko, M Narat, D Drobne - Archives of Industrial Hygiene and …, 2015 - sciendo.com
When nanoparticles enter the body, their interactions with cells are almost unavoidable.
Unintended nanoparticle interaction with immune cells may elicit a molecular response that …