Omega-3 versus omega-6 polyunsaturated fatty acids in the prevention and treatment of inflammatory skin diseases

A Balić, D Vlašić, K Žužul, B Marinović… - International journal of …, 2020 - mdpi.com
Omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) are nowadays
desirable components of oils with special dietary and functional properties. Their therapeutic …

[HTML][HTML] Stratum corneum defensive functions: an integrated view

PM Elias - Journal of Investigative Dermatology, 2005 - Elsevier
Most epidermal functions can be considered as protective, or more specifically, as defensive
in nature. Yet, the term “barrier function” is often used synonymously with only one such …

Obesity and the skin: skin physiology and skin manifestations of obesity

G Yosipovitch, A DeVore, A Dawn - Journal of the American Academy of …, 2007 - Elsevier
Obesity is widely recognized as an epidemic in the Western world; however, the impact of
obesity on the skin has received minimal attention. The purpose of this article is to highlight …

PPARs and molecular mechanisms of transrepression

M Ricote, CK Glass - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2007 - Elsevier
In the last few years, PPARs have emerged as key regulators of inflammatory and immune
responses. However, the mechanistic basis of the anti-inflammatory effects of peroxisome …

Therapeutic roles of peroxisome proliferator–activated receptor agonists

B Staels, JC Fruchart - Diabetes, 2005 - Am Diabetes Assoc
Peroxisome proliferator–activated receptors (PPARs) play key roles in the regulation of
energy homeostasis and inflammation, and agonists of PPARα and-γ are currently used …

Combinatorial roles of nuclear receptors in inflammation and immunity

CK Glass, S Ogawa - Nature Reviews Immunology, 2006 - nature.com
Members of the nuclear-receptor superfamily have well-documented regulatory effects on
inflammatory processes. Recent work has highlighted the roles of peroxisome-proliferator …

Thematic review series: skin lipids. Sebaceous gland lipids: friend or foe?

KR Smith, DM Thiboutot - Journal of lipid research, 2008 - ASBMB
Sebaceous glands are intriguing glands that are found throughout the human body except
on the palms of the hands and soles of the feet. The true function of these glands has yet to …

Psoriasis and comorbidities: links and risks

C Ni, MW Chiu - Clinical, cosmetic and investigational dermatology, 2014 - Taylor & Francis
Psoriasis is a chronic inflammatory skin disease affecting approximately 2% of the
population worldwide. In the past decade, many studies have drawn attention to comorbid …

Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis

JD Wilkinson, EM Williamson - Journal of dermatological science, 2007 - Elsevier
BACKGROUND: Cannabinoids from cannabis (Cannabis sativa) are anti-inflammatory and
have inhibitory effects on the proliferation of a number of tumorigenic cell lines, some of …

The role of transcription factor PPAR-γ in the pathogenesis of psoriasis, skin cells, and immune cells

VV Sobolev, E Tchepourina, IM Korsunskaya… - International Journal of …, 2022 - mdpi.com
The peroxisome proliferator-activated receptor PPAR-γ is one of three PPAR nuclear
receptors that act as ligand-activated transcription factors. In immune cells, the skin, and …