Wilms tumour (WT) is a childhood embryonal tumour that is paradigmatic of the intersection
between disrupted organogenesis and tumorigenesis. Many WT genes play a critical (non …

Worldwide advances in treatment and supportive care for children and adolescents with
cancer have resulted in a increasing population of survivors growing into adulthood. Yet, this …

Importance The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD
2019) provided systematic estimates of incidence, morbidity, and mortality to inform local …

Cancer statistics for adolescents and young adults (AYAs)(aged 15‐39 years) are often
presented in aggregate, masking important heterogeneity. The authors analyzed population …

The disialoganglioside GD2 is overexpressed on several solid tumors, and monoclonal
antibodies targeting GD2 have substantially improved outcomes for children with high-risk …

Advances in cancer therapeutics have revolutionized survival outcomes in patients with
cancer. However, cardiovascular toxicities associated with specific cancer therapeutics …

The aim of treating childhood cancer remains to cure all. As survival rates improve, long-
term health outcomes increasingly define quality of care. The International Childhood …

Aberrant alternative pre-mRNA splicing plays a critical role in MYC-driven cancers and
therefore may represent a therapeutic vulnerability. Here, we show that neuroblastoma, a …

Background Long-term follow-up (LTFU) care for childhood, adolescent, and young adult
(CAYA) cancer survivors is essential to preserve health and quality of life (QoL). Evidence …

Importance Improvements in cancer outcomes have led to a need to better understand long-
term oncologic and nononcologic outcomes and quantify cancer-specific vs noncancer …