Interactions between the Anopheles mosquito vector and Plasmodium parasites shape how
malaria is transmitted in endemic regions. The long association of these two organisms has …

Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

Sexual reproduction and meiotic sex are deeply rooted in the eukaryotic tree of life, but
mechanisms determining sex or mating types are extremely varied and are only well …

Plasmodium falciparum malaria drives immunoregulatory responses across multiple cell
subsets, which protects from immunopathogenesis, but also hampers the development of …

Malaria infection involves an obligatory, yet clinically silent liver stage,. Hepatocytes operate
in repeating units termed lobules, exhibiting heterogeneous gene expression patterns along …

Plasmodium falciparum secretes extracellular vesicles (Pf EVs) that contain parasite-derived
RNA. However, the significance of the secreted RNA remains unexplored. Here, we …

Abstract Development of the malaria parasite, Plasmodium falciparum, is regulated by a
limited number of sequence-specific transcription factors (TFs). However, the mechanisms …

Malaria-causing Plasmodium vivax parasites can linger in the human liver for weeks to
years and reactivate to cause recurrent blood-stage infection. Although they are an …

Plasmodium falciparum, the human malaria parasite, infects two hosts and various cell
types, inducing distinct morphological and physiological changes in the parasite in response …

The close-knit group of apicomplexan parasites displays a wide variety of cell division
modes, which differ between parasites as well as between different life stages within a …