Cancer causes the second-highest rate of death world-wide. A major shortcoming inherent
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …

Phototherapy, including photodynamic therapy and photothermal therapy, has the potential
to treat several types of cancer. However, to be an effective anticancer treatment, it has to …

Nanomedicines are extensively employed in cancer therapy. We here propose four strategic
directions to improve nanomedicine translation and exploitation.(1) Patient stratification has …

Glutathione (GSH) is the most abundant non-protein thiol, and plays crucial roles in the
antioxidant defense system and the maintenance of redox homeostasis in neurons. GSH …

In tumorous tissues, the absence of vasculature supportive tissues intimates the formation of
leaky vessels and pores (100 nm to 2 μm in diameter) and the poor lymphatic system offers …

Sonodynamic therapy (SDT) is a novel noninvasive therapeutic modality that combines low‐
intensity ultrasound and sonosensitizers. Versus photo‐mediated therapy, SDT has the …

The tumor accumulation of nanomedicines relies on the enhanced permeability and
retention (EPR) effect. In the last 5–10 years, it has been increasingly recognized that there …

The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Nanomedicines can be used for a variety of cancer therapies including tumor-targeted drug
delivery, hyperthermia, and photodynamic therapy. Poly (lactic-co-glycolic acid)(PLGA) …

Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …