Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

[HTML][HTML] Role of adherent invasive Escherichia coli in pathogenesis of inflammatory bowel disease

L Zheng, SL Duan, YC Dai, SC Wu - World journal of clinical cases, 2022 - ncbi.nlm.nih.gov
Gut microbiota imbalances play an important role in inflammatory bowel disease (IBD), but
no single pathogenic microorganism critical to IBD that is specific to the IBD terminal ileum …

[HTML][HTML] Genomic profiling of extended-spectrum β-lactamase-producing Escherichia coli from Pets in the United Arab Emirates: Unveiling colistin resistance mediated …

I Habib, M Elbediwi, K Mohteshamuddin… - Journal of Infection and …, 2023 - Elsevier
Abstract Background The United Arab Emirates (UAE) has witnessed rapid urbanization and
a surge in pet ownership, sparking concerns about the possible transfer of antimicrobial …

[HTML][HTML] Dual therapy with zinc acetate and rifaximin prevents from ethanol-induced liver fibrosis by maintaining intestinal barrier integrity

Y Fujimoto, K Kaji, N Nishimura… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Hepatic overload of gut-derived lipopolysaccharide dictates the progression
of alcoholic liver disease (ALD) by inducing oxidative stress and activating Kupffer cells and …

A single rare σ70 variant establishes a unique gene expression pattern in the E. coli pathobiont LF82

M Arroyo-Mendoza, A Proctor… - Nucleic Acids …, 2024 - academic.oup.com
LF82, an adherent-invasive Escherichia coli (AIEC) pathobiont, is associated with Crohn's
disease, an inflammatory bowel disease of unknown etiology. Although AIEC phenotypes …

Comparison of Crohn's disease-associated adherent-invasive Escherichia coli (AIEC) from France and Hong Kong: results from the Pacific study

C Chevarin, Z Xu, L Martin, F Robin, R Beyrouthy… - Gut …, 2024 - Taylor & Francis
Association between ileal colonization by Adherent-Invasive Escherichia coli (AIEC) and
Crohn's disease (CD) has been widely described in high-incidence Western countries but …

Association of Adherent-invasive Escherichia coli with severe Gut Mucosal dysbiosis in Hong Kong Chinese population with Crohn's disease

Z Xu, X Dong, K Yang, C Chevarin, J Zhang, Y Lin… - Gut …, 2021 - Taylor & Francis
ABSTRACT Adherent invasive Escherichia Coli (AIEC) has been implicated in the
pathogenesis of Crohn's disease (CD) in Western populations. Whether the presence of …

Development of prime–boost-type next-generation mucosal vaccines

K Fujimoto, S Uematsu - International immunology, 2020 - academic.oup.com
Our bodies are constantly exposed to a wide variety of pathogenic micro-organisms through
mucosal sites. Therefore, effective vaccines that can protect at the mucosa are vital; …

A consortia of clinical E. coli strains with distinct in vitro adherent/invasive properties establish their own co-colonization niche and shape the intestinal microbiota in …

RM Bleich, C Li, S Sun, JH Ahn, B Dogan, CJ Barlogio… - Microbiome, 2023 - Springer
Background Inflammatory bowel disease (IBD) patients experience recurrent episodes of
intestinal inflammation and often follow an unpredictable disease course. Mucosal …

[HTML][HTML] Vaccine therapy for dysbiosis-related diseases

K Fujimoto, S Uematsu - World Journal of Gastroenterology, 2020 - ncbi.nlm.nih.gov
Progress in genomic analysis has resulted in the proposal that the intestinal microbiota is a
crucial environmental factor in the development of multifactorial diseases, such as obesity …