GMP-manufactured CRISPR/Cas9 technology as an advantageous tool to support cancer immunotherapy

M Caforio, S Iacovelli, C Quintarelli, F Locatelli… - Journal of Experimental …, 2024 - Springer
Background CRISPR/Cas9 system to treat human-related diseases has achieved significant
results and, even if its potential application in cancer research is improving, the application …

Role of cytokine-inducible Sh2 domain-containing (CISH) protein in the regulation of erythropoiesis

S Maymand, AL Lakkavaram, W Naser, P Rasighaemi… - Biomolecules, 2023 - mdpi.com
The cytokine-inducible SH2 domain-containing (CISH) protein was the first member of the
suppressor of cytokine signaling (SOCS) family of negative feedback regulators discovered …

The mammosphere-derived epithelial cell secretome modulates neutrophil functions in the bovine model

RM Harman, A Sipka, KA Oxford, L Oliveira… - Frontiers in …, 2024 - frontiersin.org
Background Innovative therapies against bacterial infections are needed. One approach is
to focus on host-directed immunotherapy (HDT), with treatments that exploit natural …

Cish knockout mice exhibit similar outcomes to malaria infection despite altered hematopoietic responses

AL Lakkavaram, S Maymand, W Naser… - Frontiers in …, 2023 - frontiersin.org
The Cytokine-inducible Src homology 2 domain-containing (CISH) protein is a negative
feedback regulator induced by cytokines that play key roles in immunity and erythropoiesis …

Immune Factors, Immune Cells and Inflammatory Diseases

AC Ward - International Journal of Molecular Sciences, 2024 - mdpi.com
The immune system comprises distinct innate and adaptive arms, each of which contains
many layers to provide a coordinated, sequential immune response to insults [1, 2]. The cells …