Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

[HTML][HTML] EvoRegen in animals: Time to uncover deep conservation or convergence of adult stem cell evolution and regenerative processes

AG Lai, AA Aboobaker - Developmental biology, 2018 - Elsevier
How do animals regenerate specialised tissues or their entire body after a traumatic injury,
how has this ability evolved and what are the genetic and cellular components underpinning …

Xenacoelomorpha is the sister group to Nephrozoa

JT Cannon, BC Vellutini, J Smith, F Ronquist… - Nature, 2016 - nature.com
The position of Xenacoelomorpha in the tree of life remains a major unresolved question in
the study of deep animal relationships. Xenacoelomorpha, comprising Acoela …

A comprehensive analysis of bilaterian mitochondrial genomes and phylogeny

M Bernt, C Bleidorn, A Braband, J Dambach… - Molecular Phylogenetics …, 2013 - Elsevier
About 2800 mitochondrial genomes of Metazoa are present in NCBI RefSeq today, two
thirds belonging to vertebrates. Metazoan phylogeny was recently challenged by large scale …

Whole-body acoel regeneration is controlled by Wnt and Bmp-Admp signaling

M Srivastava, KL Mazza-Curll, JC van Wolfswinkel… - Current biology, 2014 - cell.com
Whole-body regeneration is widespread in the Metazoa, yet little is known about how
underlying molecular mechanisms compare across phyla. Acoels are an enigmatic phylum …

Metagenetic community analysis of microbial eukaryotes illuminates biogeographic patterns in deep‐sea and shallow water sediments

HM Bik, WAY Sung, P De Ley, JG Baldwin… - Molecular …, 2012 - Wiley Online Library
Microbial eukaryotes (nematodes, protists, fungi, etc., loosely referred to as meiofauna) are
ubiquitous in marine sediments and probably play pivotal roles in maintaining ecosystem …

Acoel single-cell atlas reveals expression dynamics and heterogeneity of adult pluripotent stem cells

RE Hulett, JO Kimura, DM Bolaños, YJ Luo… - Nature …, 2023 - nature.com
Adult pluripotent stem cell (aPSC) populations underlie whole-body regeneration in many
distantly-related animal lineages, but how the underlying cellular and molecular …

Evolution of mitochondrial gene order in Annelida

A Weigert, A Golombek, M Gerth, F Schwarz… - Molecular phylogenetics …, 2016 - Elsevier
Annelida is a highly diverse animal group with over 21,000 described species. As part of
Lophotrochozoa, the vast majority of annelids are currently classified into two groups …

Neoblasts and the evolution of whole-body regeneration

AR Gehrke, M Srivastava - Current opinion in genetics & development, 2016 - Elsevier
The molecular mechanisms underlying whole-body regeneration are best understood in the
planarian flatworm Schmidtea mediterranea, where a heterogeneous population of somatic …

A wound-induced differentiation trajectory for neurons

RE Hulett, C Rivera-López, AR Gehrke… - Proceedings of the …, 2024 - pnas.org
Animals capable of whole-body regeneration can replace any missing cell type and
regenerate fully functional new organs, including new brains, de novo. The regeneration of a …