Application of fluorescence in situ hybridization in genome analysis of the mouse

Y Matsuda, VM Chapman - Electrophoresis, 1995 - Wiley Online Library
Fluorescence in situ hybridization (FISH) is an effective technique for localizing cloned DNA
probes directly onto metaphase chromosomes. Human genome mapping using FISH has …

The Robertsonian phenomenon in the house mouse: mutation, meiosis and speciation

S Garagna, J Page, R Fernandez-Donoso, M Zuccotti… - Chromosoma, 2014 - Springer
Many different chromosomal races with reduced chromosome number due to the presence
of Robertsonian fusion metacentrics have been described in western Europe and northern …

Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2

MG Goll, F Kirpekar, KA Maggert, JA Yoder, CL Hsieh… - Science, 2006 - science.org
The sequence and the structure of DNA methyltransferase-2 (Dnmt2) bear close affinities to
authentic DNA cytosine methyltransferases. A combined genetic and biochemical approach …

Transcriptional regulatory code of a eukaryotic genome

CT Harbison, DB Gordon, TI Lee, NJ Rinaldi… - Nature, 2004 - nature.com
DNA-binding transcriptional regulators interpret the genome's regulatory code by binding to
specific sequences to induce or repress gene expression. Comparative genomics has …

The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability

MT Hemann, MA Strong, LY Hao, CW Greider - Cell, 2001 - cell.com
Loss of telomere function can induce cell cycle arrest and apoptosis. To investigate the
processes that trigger cellular responses to telomere dysfunction, we crossed mTR−/− G6 …

Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

D Bourc'his, TH Bestor - Nature, 2004 - nature.com
Mammalian genomes employ heritable cytosine methylation in the long-term silencing of
retrotransposons and genes subject to genomic imprinting and X chromosome inactivation …

A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite.

H Masumoto, H Masukata, Y Muro, N Nozaki… - The Journal of cell …, 1989 - rupress.org
We report the interaction between a human centromere antigen and an alphoid DNA, a
human centromeric satellite DNA, which consists of 170-bp repeating units. A cloned …

Hypervariable ultra-long telomeres in mice

D Kipling, HJ Cooke - Nature, 1990 - nature.com
TELOMERE structure and behaviour is less well understood in vertebrates than it is in
ciliates and yeasts (reviewed in ref. 1). Like all other eukaryotic chromosomes, those of …

Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice

EV Howman, KJ Fowler, AJ Newson… - Proceedings of the …, 2000 - National Acad Sciences
Centromere protein A (Cenpa for mouse, CENP-A for other species) is a histone H3-like
protein that is thought to be involved in the nucleosomal packaging of centromeric DNA …

[HTML][HTML] Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells

M Tada, T Tada, L Lefebvre, SC Barton… - The EMBO journal, 1997 - embopress.org
Genomic reprogramming of primordial germ cells (PGCs), which includes genome‐wide
demethylation, prevents aberrant epigenetic modifications from being transmitted to …