Peripheral nerve injury and axonotmesis: State of the art and recent advances

R Alvites, A Rita Caseiro, S Santos Pedrosa… - Cogent …, 2018 - Taylor & Francis
Peripheral nerve lesions are frequent occurrences in both human and animal patients,
leading to important physiological and labor complications that affect the quality of life of …

Schwann cell transplantation for repair of the adult spinal cord

M Oudega, XM Xu - Journal of neurotrauma, 2006 - liebertpub.com
The Schwann cell is one of the most widely studied cell types for repair of the spinal cord.
These cells play a crucial role in endogenous repair of peripheral nerves due to their ability …

Key changes in denervated muscles and their impact on regeneration and reinnervation

P Wu, A Chawla, RJ Spinner, C Yu… - Neural regeneration …, 2014 - journals.lww.com
The neuromuscular junction becomes progressively less receptive to regenerating axons if
nerve repair is delayed for a long period of time. It is difficult to ascertain the denervated …

Reinnervation of the tibialis anterior following sciatic nerve crush injury: a confocal microscopic study in transgenic mice

CK Magill, A Tong, D Kawamura, A Hayashi… - Experimental …, 2007 - Elsevier
Transgenic mice whose axons and Schwann cells express fluorescent chromophores
enable new imaging techniques and augment concepts in developmental neurobiology. The …

Electrical stimulation facilitates rat facial nerve recovery from a crush injury

D Lal, LT Hetzler, N Sharma… - … —Head and Neck …, 2008 - journals.sagepub.com
Objective To study the effect of electrical stimulation on accelerating facial nerve functional
recovery from a crush injury in the rat model. Study Design Experimental. Method The main …

Characterization of tests of functional recovery after median and ulnar nerve injury and repair in the rat forelimb

CM Galtrey, JW Fawcett - Journal of the Peripheral Nervous …, 2007 - Wiley Online Library
The majority of human peripheral nerve injuries occur in the upper limb but the majority of
studies in the rat are performed in the hindlimb. The upper and lower limbs differ in dexterity …

Polyethylene glycol rapidly restores axonal integrity and improves the rate of motor behavior recovery after sciatic nerve crush injury

JM Britt, JR Kane, CS Spaeth, A Zuzek… - Journal of …, 2010 - journals.physiology.org
The inability to rapidly (within minutes to hours) improve behavioral function after severance
of peripheral nervous system axons is an ongoing clinical problem. We have previously …

Electrophysiologic and functional evaluations of regenerated facial nerve defects with a tube containing dental pulp cells in rats

R Sasaki, H Matsumine, Y Watanabe… - Plastic and …, 2014 - journals.lww.com
Background: Dental pulp tissue contains Schwann and neural progenitor cells. Tissue-
engineered nerve conduits with dental pulp cells promote facial nerve regeneration in rats …

Dental pulp cell sheets enhance facial nerve regeneration via local neurotrophic factor delivery

MN Ahmed, D Shi, MT Dailey… - … Engineering Part A, 2021 - liebertpub.com
An effective strategy for sustained neurotrophic factor (NTF) delivery to sites of peripheral
nerve injury (PNI) would accelerate healing and enhance functional recovery, addressing …

Hypoxic Bone Mesenchymal Stem Cell-Derived Exosomes Direct Schwann Cells Proliferation, Migration, and Paracrine to Accelerate Facial Nerve Regeneration via …

H Wang, H Zhao, Z Chen, X Cai, X Wang… - International Journal …, 2024 - Taylor & Francis
Background Facial nerves have the potential for regeneration following injury, but this
process is often challenging and slow. Schwann cells (SCs) are pivotal in this process. Bone …