New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …

BACKGROUND Historical accounts linking cancer and microbes date as early as four
millennia ago. After establishment of the germ theory of infectious diseases, clinical research …

Although polymorphic microbiomes have emerged as hallmarks of cancer, far less is known
about the role of the intratumor mycobiome as living microorganisms in cancer progression …

In lung cancer, enrichment of the lower airway microbiota with oral commensals commonly
occurs, and ex vivo models support that some of these bacteria can trigger host …

The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

The present review is an update of the research and development efforts regarding the use
of molecular biomarkers in the lung cancer screening setting. The two main unmet clinical …

Although intestinal microbiome have been established as an important biomarker and
regulator of cancer development and therapeutic response, less is known about the role of …

The trillions of microorganisms in the gut microbiome have attracted much attention recently
owing to their sophisticated and widespread impacts on numerous aspects of host …

Background Lung cancer is the leading cause of cancer-related deaths worldwide (Ferlay et
al., Int J Cancer 136: E359–386, 2015). In addition, lung cancer is associated with the …

It is estimated that in the future, the number of new cancer cases worldwide will exceed the
19.3 million recorded in 2020, and the number of deaths will exceed 10 million. Cancer …