Microorganisms are a fundamental part of virtually every ecosystem on earth. Understanding
how collectively they interact, assemble, and function as communities has become a …

The prediction of genes related to diseases is important to the study of the diseases due to
high cost and time consumption of biological experiments. Network propagation is a popular …

Protein kinases play an important role in cellular signaling pathways and their dysregulation
leads to multiple diseases, making kinases prime drug targets. While more than 500 human …

Understanding the function of cellular systems requires describing how proteins assemble
with each other into transient and stable complexes and to determine their spatial …

Construction of empirical fitness landscapes has transformed our understanding of genotype–
phenotype relationships across genes. However, most empirical fitness landscapes have …

Finding new methods to study the effect of small molecules on protein interaction networks
provides us with invaluable tools in the fields of pharmacodynamics and drug design …

In 2021, the 100th anniversary of the isolation of insulin and the rescue of a child with type 1
diabetes from death will be marked. In this review, we highlight advances since the …

Protein interactions link genotypes to phenotypes. Although phenotypes are known to
depend on environmental context, the response of protein interactions to environmental …

Résumé Les interactions protéine-protéine (PPI) sont à la base du fonctionnement cellulaire
de tous les organismes. Regroupées en deux catégories, les méthodes pour étudier les PPI …