An attractive path forward in proteomics is to experimentally annotate the human protein
complement of the genome in a genecentric manner. Using antibodies, it might be possible …

The Omicron, the latest variant of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), was first detected in November 2021 in Botswana, South Africa. Compared to other …

Serum antibodies can recognize both pathogens and commensal gut microbiota. However,
our current understanding of antibody repertoires is largely based on DNA sequencing of …

Antibodies are useful tools to characterize the components of the human proteome and to
validate potential protein biomarkers discovered through various clinical proteomics efforts …

The tendency to use the terms homology, similarity, and identity interchangeably persists in
comparative biology. When translated to immunology, overlapping the concepts of …

Reducing amyloid-β peptide (Aβ) burden at the pre-symptomatic stages of Alzheimer's
disease (AD) is currently the advocated clinical strategy for treating this disease. The most …

High grade gliomas are the most common brain tumors in adults and their malignant nature
makes them the fourth biggest cause of cancer death. Major efforts in neuro-oncology …

CRISPR-inspired systems have been extensively developed for applications in genome
editing and nucleic acid detection. Here, we introduce a CRISPR-based peptide display …

In biology, localisation is function: knowledge of the localisation of proteins is of paramount
importance to assess and study their function. This supports the need for reliable protein sub …

Affinity proteomics is the field of proteome analysis based on the use of antibodies and other
binding reagents as protein-specific detection probes. In this review, the particular strengths …