Micronuclei (MN), the small nucleus-like bodies separated from the primary nucleus, can
exist in cells with numerical and/or structural chromosomal aberrations in apparently normal …

Micronuclei are constantly considered as a marker of genome instability and very recently
found to be a trigger of innate immune responses. An increased frequency of micronuclei is …

Mitomycin C (MMC) is an alkylating chemotherapy drug that causes DNA crosslinking
resulting in transcription arrest and apoptosis. DNA crosslinking is a critical damage to DNA …

The evaluation of genotoxicity is a fundamental part of the safety assessment of chemicals
due to the relevance of the potential health effects of genotoxicants. Among the testing …

Coronary artery disease (CAD) is the leading cause of morbidity and mortality worldwide.
Coronary angiography allows an accurate assessment of the extent and severity of …

Multitude of diseases and side effects from conventional drugs have surged the use of
herbal remedies. Thus, the current study aimed to appraise various pharmacological …

Erythropoietin (EPO) applies anti-inflammatory, anti-apoptotic, anti-oxidant and
cytoprotective effects besides its hematopoietic action. A nonhematopoietic peptide …

Few studies have investigated the association between herbal medicine consumption and
coronary artery disease severity. This cross‐sectional study aimed to investigate the …

Objective: To explore the mechanism of Shengmai Yin (SMY) for coronary heart disease
(CHD) by systemic pharmacology and chemoinformatics. Methods: Traditional Chinese …

Ionizing radiation leads to the development of oxidative stress and damage to biologically
important macromolecules (DNA, mitochondria, etc.), which in turn lead to cell death. In the …