The role of non-invasive respiratory support (high-flow nasal oxygen and noninvasive
ventilation) in the management of acute hypoxemic respiratory failure and acute respiratory …

Patients with severe lung injury usually have a high respiratory drive, resulting in intense
inspiratory effort that may even worsen lung damage by several mechanisms gathered …

Background Insufficient or excessive respiratory effort during acute hypoxemic respiratory
failure (AHRF) increases the risk of lung and diaphragm injury. We sought to establish …

There is a well-recognised importance for personalising mechanical ventilation settings to
protect the lungs and the diaphragm for each individual patient. Measurement of …

Background Few specific methods are available to reduce the risk of diaphragmatic
dysfunction for patients under mechanical ventilation. The number of studies involving …

OBJECTIVES: Lung-and diaphragm-protective ventilation is a novel concept that aims to
limit the detrimental effects of mechanical ventilation on the diaphragm while remaining …

Background Patient–ventilator asynchrony (PVA) is a common problem in patients
undergoing invasive mechanical ventilation (MV) in the intensive care unit (ICU), and may …

Weaning is a critical stage of an intensive care unit (ICU) stay, in which the respiratory
muscles play a major role. Weakness of the respiratory muscles, which is associated with …

Rationale: Hypoxemia during mechanical ventilation might be worsened by expiratory
muscle activity, which reduces end-expiratory lung volume through lung collapse. A …