Electrochemical biosensors for whole blood analysis: recent progress, challenges, and future perspectives

S Li, H Zhang, M Zhu, Z Kuang, X Li, F Xu… - Chemical …, 2023 - ACS Publications
Whole blood, as one of the most significant biological fluids, provides critical information for
health management and disease monitoring. Over the past 10 years, advances in …

Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Cancer diagnosis: from tumor to liquid biopsy and beyond

R Vaidyanathan, RH Soon, P Zhang, K Jiang, CT Lim - Lab on a Chip, 2019 - pubs.rsc.org
Technological advancements in research on circulating biomarkers from patient derived
blood have enabled a less invasive means of diagnosing non-hematologic cancers …

Circulating tumor DNA and liquid biopsy: opportunities, challenges, and recent advances in detection technologies

L Gorgannezhad, M Umer, MN Islam, NT Nguyen… - Lab on a Chip, 2018 - pubs.rsc.org
Cell-free DNA (cfDNA) refers to short fragments of acellular nucleic acids detectable in
almost all body fluids, including blood, and is involved in various physiological and …

Recent advances on electrochemical biosensing strategies toward universal point‐of‐care systems

Y Dai, CC Liu - Angewandte Chemie, 2019 - Wiley Online Library
A number of very recently developed electrochemical biosensing strategies are promoting
electrochemical biosensing systems into practical point‐of‐care applications. The focus of …

Emerging biosensing and transducing techniques for potential applications in point-of-care diagnostics

J Qin, W Wang, L Gao, SQ Yao - Chemical Science, 2022 - pubs.rsc.org
With the deepening of our understanding in life science, molecular biology, nanotechnology,
optics, electrochemistry and other areas, an increasing number of biosensor design …

Advanced liquid biopsy technologies for circulating biomarker detection

N Soda, BHA Rehm, P Sonar, NT Nguyen… - Journal of Materials …, 2019 - pubs.rsc.org
Liquid biopsy is a new diagnostic concept that provides important information for monitoring
and identifying tumor genomes in body fluid samples. Detection of tumor origin …

Scalable COVID-19 detection enabled by lab-on-chip biosensors

C Tymm, J Zhou, A Tadimety, A Burklund… - Cellular and molecular …, 2020 - Springer
Introduction The emergence of a novel coronavirus, SARS-CoV-2, has highlighted the need
for rapid, accurate, and point-of-care diagnostic testing. As of now, there is not enough …

DNA electrochemistry and electrochemical sensors for nucleic acids

EE Ferapontova - Annual review of analytical chemistry, 2018 - annualreviews.org
Sensitive, specific, and fast analysis of nucleic acids (NAs) is strongly needed in medicine,
environmental science, biodefence, and agriculture for the study of bacterial contamination …