Background Vitamin K antagonists are the only oral anticoagulants approved to prevent
valve thrombosis and valve-related thromboembolism in patients with mechanical heart …

In the recent years, there has been significant transformation in the management of valvular
heart disease (VHD), as a result of new minimally invasive technologies, such as the …

Valvular heart disease is a common disease often necessitating valve replacement.
Mechanical heart valves (MHVs) are often used in younger patients because of their longer …

Background Vitamin K antagonists are the only approved oral anticoagulants for long-term
prophylaxis against valve thrombosis and thromboembolism in patients with a mechanical …

Purpose To determine the risk of mechanical vessel wall damage resulting in hemorrhage
during and after hepatic and renal histotripsy in an anticoagulated in vivo porcine model …

Abstract Background and Purpose To date, vitamin K antagonists are the only available oral
anticoagulants in patients with mechanical heart valves. In this way, we developed a pilot …

Importance Current international normalized ratio (INR) guidelines are based on trials
involving European and US populations. To our knowledge, no adequate study involving …

What is known and objective Direct oral anticoagulants (DOACs) are increasingly prescribed
instead of warfarin for chronic anticoagulation for ease of dosing, fewer interactions, and …

Abstract Purpose of Review The anticoagulation strategies for various cardiac-specific
pathologies including atrial fibrillation are changing. Applying these strategies in patients …

e160 Arterioscler Thromb Vasc Biol June 2019 we have tried to elucidate the pathogenesis
of this disorder. Importantly, plasma levels of TAFI (also known as carboxypeptidase B2 …