C-type lectin receptors (CLRs) are important pattern recognition receptors involved in
recognition and induction of adaptive immunity to pathogens. Certain CLRs play an …

The complement system plays a critical role in innate immune defense against pathogens,
both via non-specific direct pathogen recognition and killing or via antigen-specific indirect …

Components of the complement system and atypical parameters of coagulation were
reported in COVID-19 patients, as well as the exacerbation of the inflammation and …

Background Non-neutralising antibodies to the envelope glycoprotein are elicited during
acute HIV-1 infection and are abundant throughout the course of disease progression …

Generation of Human Monocyte-derived Dendritic Cells from Whole Blood - PMC Back to Top
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

The complement system, a key component of innate immunity, is a first-line defender against
foreign pathogens such as HIV-1. The role of the complement system in HIV-1 pathogenesis …

The human immunodeficiency virus type 1 (HIV-1) is an enveloped retrovirus that undergoes
assembly at specific sites in infected cells. In macrophages, at least, this assembly occurs …

Since the 1990s we have known of the fascinating ability of a complex set of professional
antigen presenting cells (APCs; dendritic cells, monocytes/macrophages, and B …

Dendritic cells (DC) are crucial components of the early events of HIV infection. Dendritic
cells capture and internalize HIV at mucosal surfaces and efficiently transfer the virus to …

Immature dendritic cells (iDCs) in genital and rectal mucosa may be one of the first cells to
come into contact with HIV-1 during sexual transmission of virus. HIV-1 activates the host …