Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that
is associated with poor survival. The International Society for Heart and Lung …

Allograft failure remains a major barrier in the field of lung transplantation and results
primarily from acute and chronic rejection. To date, standard-of-care immunosuppressive …

The last decade has seen development of oral, small molecule therapies that address the
basic cystic fibrosis transmembrane conductance regulator (CFTR) protein defect. Highly …

Background Alterations in the respiratory microbiome are common in chronic lung diseases,
correlate with decreased lung function, and have been associated with disease progression …

Background Prior studies have shown that patients with pulmonary fibrosis with mutations in
the telomerase genes have a high rate of certain complications after lung transplantation …

Background Bronchiolitis obliterans syndrome (BOS) is the major cause of late graft failure
after lung transplantation. The objective was to determine whether de novo donor human …

Background Transbronchial biopsies using standard forceps (FTBBxs) are often limited by
crush artifact and their small size. To date, there have been no studies aimed at assessing …

Lung transplantation is the only viable option for patients suffering from otherwise incurable
end-stage pulmonary diseases such as chronic obstructive pulmonary disease and …

Background The relationship between community-acquired respiratory viruses (CARVs) and
chronic lung allograft dysfunction (CLAD) in lung transplant recipients is still controversial …

Acute allograft rejection remains a prevalent and serious problem in lung transplantation,
with an incidence of 36% in the first year after transplant according to the latest report from …