Over the past decades, the bulk of chemists' interests have been on heterocyclic compounds
and their various derivatives as well as their applications in the pharmaceutical and …

Many compounds containing a five‐membered heterocyclic ring display exceptional
chemical properties and versatile biological activities. In this Minireview, thiadiazoles are …

In spite of substantial progress made toward understanding cancer pathogenesis, this
disease remains one of the leading causes of mortality. Thus, there is an urgent need to …

Significant progress in understanding cancer pathogenesis, it remains one of the leading
causes of death after cardiovascular diseases. Similarly viral infections have emerged from …

In an attempt to develop potent antitumor agents, new 1, 3, 4-thiadiazole derivatives were
synthesized and evaluated for their cytotoxic effects on multiple human cancer cell lines …

We designed and synthesized the 1, 3, 4-thiadiazole derivatives differing in the structure of
the substituents in C2 and C5 positions. The cytotoxic activity of the obtained compounds …

Background Nowadays, cancer is an important public health problem in all countries.
Limitations of current chemotherapy for neoplastic diseases such as severe adverse …

The chemistry of 1, 3, 4-thiadiazoles is very well known. A universal and commonly used
method of the synthesis of different 2, 5-disubstituted 1, 3, 4-thiadiazoles includes the …

Objective (s): Nowadays, cancer is an important public health problem in all countries.
Limitations of current chemotherapy for neoplastic diseases such as severe adverse …

Extensive investigation on the molecular and electronic structure of 2-amino-5-
trifluoromethyl-1, 3, 4-thiadiazole in the ground state and in the first excited state has been …