Osteoarthritis (OA) is the most common form of arthritis and a major cause of pain and
disability in older adults (1). Often OA is referred to as degenerative joint disease “(DJD)” …

Raman spectroscopy is increasingly commonly used to understand how changes in bone
composition and structure influence tissue-level bone mechanical properties. The …

Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral
density (BMD). We assessed genetic determinants of BMD as estimated by heel quantitative …

As the GFR loss aggravates, the disturbed mineral metabolism worsens the bone
microstructure and remodelling‐scenario, which is known as CKD‐mineral bone disease …

Background The skeleton plays a critical structural role in bearing functional loads, and
failure to do so results in fracture. As we evaluate new therapeutics and consider treatments …

Raman spectroscopy (RS) is used to analyze the physiochemical properties of bone
because it is non-destructive and requires minimal sample preparation. With over two …

Tendon attaches to bone across a functionally graded interface,“the enthesis”. A gradient of
mineral content is believed to play an important role for dissipation of stress concentrations …

Alterations in the gut microbiome have been associated with changes in bone mass and
microstructure, but the effects of the microbiome on bone biomechanical properties are not …

Abstract Purpose of Review While thinning of the cortices or trabeculae weakens bone, age-
related changes in matrix composition also lower fracture resistance. This review …

Vertebral strength, as estimated by finite element analysis of computed tomography (CT)
scans, has not yet been compared against areal bone mineral density (BMD) by dual …