Obesity, hypertension, and cardiac dysfunction: novel roles of immunometabolism in macrophage activation and inflammation

AJ Mouton, X Li, ME Hall, JE Hall - Circulation research, 2020 - Am Heart Assoc
Obesity and hypertension, which often coexist, are major risk factors for heart failure and are
characterized by chronic, low-grade inflammation, which promotes adverse cardiac …

Mitophagy in human diseases

L Doblado, C Lueck, C Rey, AK Samhan-Arias… - International journal of …, 2021 - mdpi.com
Mitophagy is a selective autophagic process, essential for cellular homeostasis, that
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …

Turmeric and its bioactive constituents trigger cell signaling mechanisms that protect against diabetes and cardiovascular diseases

HA Zhang, DD Kitts - Molecular and cellular biochemistry, 2021 - Springer
Turmeric, the rhizome of Curcuma longa plant belonging to the ginger family Zingiberaceae,
has a history in Ayurvedic and traditional Chinese medicine for treatment of chronic …

Lipid peroxidation in atherosclerotic cardiovascular diseases

E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …

NRF2 in cardiovascular diseases: a ray of hope!

R Vashi, BM Patel - Journal of cardiovascular translational research, 2021 - Springer
Heart failure is a worldwide pandemic influencing 26 million individuals worldwide and is
expanding. Imbalanced redox homeostasis in cardiac cells alters the structure and function …

Cardiovascular changes associated with hypertensive heart disease and aging

S Saheera, P Krishnamurthy - Cell transplantation, 2020 - journals.sagepub.com
Cardiovascular diseases are the leading cause of mortality and morbidity worldwide and
account for more than 17.9 million deaths (World Health Organization report). Hypertension …

Diabetic cardiomyopathy: 2023 update by the international multidisciplinary board of experts

A Avagimyan, F Fogacci, N Pogosova… - Current Problems in …, 2024 - Elsevier
Diabetes mellitus (DM) is considered by many the pandemic of the 21st century and is
associated with multiple organ damages. Among these, cardiovascular complications are …

The Hippo signaling pathway in cardiac development and diseases

MM Mia, MK Singh - Frontiers in cell and developmental biology, 2019 - frontiersin.org
Heart disease continues to be the leading cause of morbidity and mortality worldwide.
Cardiac malformation during development could lead to embryonic or postnatal death …

TRAF molecules in inflammation and inflammatory diseases

AI Lalani, S Zhu, S Gokhale, J Jin, P Xie - Current Pharmacology Reports, 2018 - Springer
Abstract Purpose of Review This review presents an overview of the current knowledge of
tumor necrosis factor receptor (TNF-R)-associated factor (TRAF) molecules in inflammation …

MiR-223-3p in cardiovascular diseases: a biomarker and potential therapeutic target

MW Zhang, YJ Shen, J Shi, JG Yu - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Cardiovascular diseases, involving vasculopathy, cardiac dysfunction, or circulatory
disturbance, have become the major cause of death globally and brought heavy social …