Trypanosoma brucei is a pathogenic unicellular eukaryote that infects humans and other
mammals in sub-Saharan Africa. A central feature of trypanosome biology is the single …

African trypanosomes are sustained in the bloodstream of their mammalian hosts by their
extreme capacity for antigenic variation. However, for life cycle progression, trypanosomes …

The protozoan parasites Trypanosoma brucei spp. cause important human and livestock
diseases in sub-Saharan Africa. In mammalian blood, two developmental forms of the …

Trypanosome parasites control their virulence and spread by using quorum sensing (QS) to
generate transmissible" stumpy forms" in their host bloodstream. However, the QS signal" …

African trypanosomes cause devastating disease in sub-Saharan Africa in humans and
livestock. The parasite lives extracellularly within the bloodstream of mammalian hosts and …

Primary ciliary dyskinesia (PCD) is a hereditary genetic disorder caused by the lack of motile
cilia or the assembxly of dysfunctional ones. This rare human disease affects 1 out of 10,000 …

The peritrophic matrix of blood-feeding insects is a chitinous structure that forms a protective
barrier against oral pathogens and abrasive particles. Tsetse flies transmit Trypanosoma …

Developmental regulation of mitochondrial uridine insertion/deletion editing in Trypanosoma
brucei is necessary to modulate parasite metabolism as it shifts from dependence on …

The sleeping sickness parasite, Trypanosoma brucei, uses quorum sensing (QS) to balance
proliferation and transmission potential in the mammal bloodstream. A signal transduction …

Adaptation to a change of environment is an essential process for survival, in particular for
parasitic organisms exposed to a wide range of hosts. Such adaptations include rapid …