Extein residues regulate the catalytic function of Spl DnaX intein enzyme by restricting the near‐attack conformations of the active‐site residues
Intein enzymes catalyze the splicing of their flanking polypeptide chains and have found
tremendous biotechnological applications. Their terminal residues form the catalytic core …
tremendous biotechnological applications. Their terminal residues form the catalytic core …
Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules
Q Li, C Kang - FEBS letters, 2023 - Wiley Online Library
RNA‐binding proteins (RBPs) play vital roles in organisms through binding with RNAs to
regulate their functions. Small molecules affecting the function of RBPs have been …
regulate their functions. Small molecules affecting the function of RBPs have been …
[HTML][HTML] Identification of potential short linear motifs (SLiMs) in intrinsically disordered sequences of proteins by fast time-scale backbone dynamics
Intrinsically disordered regions (IDRs) of proteins contain functionally important short linear
motifs (SLiMs), which are composed of 3 to 10 residues. They are often crucial members in …
motifs (SLiMs), which are composed of 3 to 10 residues. They are often crucial members in …
Cold-shock proteome of myoblasts reveals role of RBM3 in promotion of mitochondrial metabolism and myoblast differentiation
P Dey, S Rajalaxmi, P Saha, PS Thakur… - Communications …, 2024 - nature.com
Adaptation to hypothermia is important for skeletal muscle cells under physiological stress
and is used for therapeutic hypothermia (mild hypothermia at 32° C). We show that …
and is used for therapeutic hypothermia (mild hypothermia at 32° C). We show that …
[PDF][PDF] Current Research in Structural Biology
A Singh, B Acharya, B Mukherjee… - Current Research in …, 2024 - researchgate.net
Extradenticle (EXD) is a partner protein of the HOX transcription factors and plays an
important role in the development of Drosophila. It confers increased affinity and specificity …
important role in the development of Drosophila. It confers increased affinity and specificity …
Nuclear magnetic resonance spectroscopy to Analyse protein folding and dynamics
Proteins are nanoscale machines that perform all the work in living systems. Their function
depends on their three-dimensional (3D) structure. These nanomachines are manufactured …
depends on their three-dimensional (3D) structure. These nanomachines are manufactured …
[HTML][HTML] Stability and dynamics of extradenticle modulates its function
Extradenticle (EXD) is a partner protein of the HOX transcription factors and plays an
important role in the development of Drosophila. It confers increased affinity and specificity …
important role in the development of Drosophila. It confers increased affinity and specificity …
低温诱导的RBM3 对各器官缺血再灌注损伤研究进展.
孙路轩， 党晓平， 孙子健 - Journal of New Medicine, 2024 - search.ebscohost.com
缺血再灌注损伤(IRI) 是一种复杂的血流动力学紊乱状态, 致死率极高, 且目前的治疗方法相对
有限. 亚低温治疗是临床上公认的一种缓解缺血, 缺氧损伤的治疗方式, 尤其在脑保护中的研究较 …
有限. 亚低温治疗是临床上公认的一种缓解缺血, 缺氧损伤的治疗方式, 尤其在脑保护中的研究较 …
and Soumya De D
NV Saibo, S Boral, R Saha, AK Das - Protein Folding Dynamics …, 2023 - books.google.com
Proteins are nanoscale machines that perform all the work in living systems. Their function
depends on their three-dimensional (3D) structure. These nanomachines are manufactured …
depends on their three-dimensional (3D) structure. These nanomachines are manufactured …