Background.—Under the auspices of the College of American Pathologists, a
multidisciplinary group of clinicians, pathologists, and statisticians considered prognostic …

Chromosome instability (CIN) is gaining increasing interest as a central process in cancer.
CIN, either past or present, is indicated whenever tumour cells harbour an abnormal quantity …

From the reviews of the 3rd Edition..." The standard reference for anyone interested in
understanding flow cytometry technology." American Journal of Clinical Oncology"... one of …

Background The efficacy of surgery for patients with non-small-cell lung cancer is limited,
although recent studies suggest that preoperative chemotherapy may improve survival. We …

Aneuploidy is associated with poor prognosis in solid tumors. Spontaneous chromosome
missegregation events in aneuploid cells promote chromosomal instability (CIN) that may …

Mucinous cystic neoplasms (MCNs) of the pancreas are uncommon tumors. The
classification and biologic potential of these neoplasms remain the subject of controversy …

These consensual guidelines and recommendations address the potential utility of DNA
cytometry in characterizing human malignancies. They are provided to inform laboratory …

Flow cytometric DNA analysis was used to study changes in nuclear DNA content induced
by the addition of complete or telosomic rye chromosomes into the genome of common …

SHP-2 is a protein tyrosine phosphatase functioning as signal transducer downstream to
growth factor and cytokine receptors. SHP-2 is required during development, and germline …

The molecular approach for the analysis of leukemia associated chromosomal
translocations has led to the identification of prognostic relevant subgroups. In pediatric …