Incomplete immune recovery in HIV infection: mechanisms, relevance for clinical care, and possible solutions
JC Gaardbo, HJ Hartling, J Gerstoft… - Journal of Immunology …, 2012 - Wiley Online Library
Treatment of HIV‐infected patients with highly active antiretroviral therapy (HAART) usually
results in diminished viral replication, increasing CD4+ cell counts, a reversal of most …
results in diminished viral replication, increasing CD4+ cell counts, a reversal of most …
Initiation of antiretroviral therapy in early asymptomatic HIV infection
Insight Start Study Group - New England Journal of Medicine, 2015 - Mass Medical Soc
Background Data from randomized trials are lacking on the benefits and risks of initiating
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled …
B Grinsztejn, MC Hosseinipour, HJ Ribaudo… - The Lancet infectious …, 2014 - thelancet.com
Background Use of antiretroviral treatment for HIV-1 infection has decreased AIDS-related
morbidity and mortality and prevents sexual transmission of HIV-1. However, the best time to …
morbidity and mortality and prevents sexual transmission of HIV-1. However, the best time to …
Antiviral agents and HIV prevention: controversies, conflicts, and consensus
Antiviral agents can be used to prevent HIV transmission before exposure as preexposure
prophylaxis (PrEP), after exposure as postexposure prophylaxis, and as treatment of …
prophylaxis (PrEP), after exposure as postexposure prophylaxis, and as treatment of …
[HTML][HTML] Effect of early versus deferred antiretroviral therapy for HIV on survival
MM Kitahata, SJ Gange, AG Abraham… - … England Journal of …, 2009 - Mass Medical Soc
Background The optimal time for the initiation of antiretroviral therapy for asymptomatic
patients with human immunodeficiency virus (HIV) infection is uncertain. Methods We …
patients with human immunodeficiency virus (HIV) infection is uncertain. Methods We …
Late presentation of HIV infection: a consensus definition
A Antinori, T Coenen, D Costagiola, N Dedes… - HIV …, 2011 - Wiley Online Library
Objectives Across Europe, almost a third of individuals infected with HIV do not enter health
care until late in the course of their infection. Surveillance to identify the extent to which late …
care until late in the course of their infection. Surveillance to identify the extent to which late …
Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society–USA panel
SM Hammer, JJ Eron, P Reiss, RT Schooley… - Jama, 2008 - jamanetwork.com
Context The availability of new antiretroviral drugs and formulations, including drugs in new
classes, and recent data on treatment choices for antiretroviral-naive and-experienced …
classes, and recent data on treatment choices for antiretroviral-naive and-experienced …
The therapeutic implications of timely linkage and early retention in HIV care
KB Ulett, JH Willig, HY Lin, JS Routman… - AIDS patient care and …, 2009 - liebertpub.com
Following HIV diagnosis, linkage to outpatient treatment, antiretroviral initiation, and
longitudinal retention in care represent the foundation for successful treatment. While prior …
longitudinal retention in care represent the foundation for successful treatment. While prior …
All-cause mortality in treated HIV-infected adults with CD4 ≥500/mm3 compared with the general population: evidence from a large European observational cohort …
Collaboration of Observational HIV … - International journal …, 2012 - academic.oup.com
Background Using data from a large European collaborative study, we aimed to identify the
circumstances in which treated HIV-infected individuals will experience similar mortality …
circumstances in which treated HIV-infected individuals will experience similar mortality …
When to initiate combined antiretroviral therapy to reduce mortality and AIDS-defining illness in HIV-infected persons in developed countries: an observational study
HIV-CAUSAL Collaboration* - Annals of internal medicine, 2011 - acpjournals.org
Background: Most clinical guidelines recommend that AIDS-free, HIV-infected persons with
CD4 cell counts below 0.350× 109 cells/L initiate combined antiretroviral therapy (cART), but …
CD4 cell counts below 0.350× 109 cells/L initiate combined antiretroviral therapy (cART), but …