Helminths and their implication in sepsis–a new branch of their immunomodulatory behaviour?
The prevalence of autoimmune and allergic disorders has dramatically increased in
developed countries, and it is believed that our 'cleaner living'reduces exposure to certain …
developed countries, and it is believed that our 'cleaner living'reduces exposure to certain …
Filariasis research–from basic research to drug development and novel diagnostics, over a decade of research at the Institute for Medical Microbiology, Immunology …
Filariae are vector borne parasitic nematodes, endemic in tropical and subtropical regions
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …
Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils
SJ Frohberger, J Ajendra, J Surendar, W Stamminger… - Parasites & vectors, 2019 - Springer
Background Mice are susceptible to infections with the rodent filarial nematode
Litomosoides sigmodontis and develop immune responses that resemble those of human …
Litomosoides sigmodontis and develop immune responses that resemble those of human …
Concurrent Infection With the Filarial Helminth Litomosoides sigmodontis Attenuates or Worsens Influenza A Virus Pathogenesis in a Stage-Dependent Manner
GR Hardisty, JA Knipper, A Fulton, J Hopkins… - Frontiers in …, 2022 - frontiersin.org
Filarial helminths infect approximately 120 million people worldwide initiating a type 2
immune response in the host. Influenza A viruses stimulate a virulent type 1 pro …
immune response in the host. Influenza A viruses stimulate a virulent type 1 pro …
Nematode-induced interference with vaccination efficacy targets follicular T helper cell induction and is preserved after termination of infection
One-third of the human population is infected with parasitic worms. To avoid being
eliminated, these parasites actively dampen the immune response of their hosts. This …
eliminated, these parasites actively dampen the immune response of their hosts. This …
Pathogenic nematodes suppress humoral responses to third-party antigens in vivo by IL-10–mediated interference with Th cell function
W Hartmann, I Haben, B Fleischer… - The Journal of …, 2011 - journals.aai.org
One third of the human population is infected with helminth parasites. To promote their
longevity and to limit pathology, helminths have developed several strategies to suppress …
longevity and to limit pathology, helminths have developed several strategies to suppress …
[HTML][HTML] Parasites induced skin allergy: a strategic manipulation of the host immunity
AH Bakiri, EC Mingomataj - Journal of clinical medicine research, 2010 - ncbi.nlm.nih.gov
The absence of a consistent link between parasitoses and skin allergic symptoms in the
clinical investigations contrasts to the fact that some parasites are the most potent inducers …
clinical investigations contrasts to the fact that some parasites are the most potent inducers …
Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during Litomosoides sigmodontis filarial infection
E Remion, J Gal, S Chaouch, J Rodrigues… - Frontiers in …, 2022 - frontiersin.org
Filarial parasites are tissue dwelling worms transmitted by hematophagous vectors.
Understanding the mechanisms regulating microfilariae (the parasite offspring) development …
Understanding the mechanisms regulating microfilariae (the parasite offspring) development …
Differences of in vitro immune responses between patent and pre-patent Litomosoides sigmodontis–infected mice are independent of the filarial antigenic stimulus …
K Arndts, A Wiszniewsky, AL Neumann… - Parasitology …, 2024 - Springer
Lymphatic filariasis and onchocerciasis are neglected tropical diseases and cause
significant public health problems in endemic countries, especially in sub-Saharan Africa …
significant public health problems in endemic countries, especially in sub-Saharan Africa …
Lipopolysaccharide-induced acute lung injury in mice chronically infected by Schistosoma mansoni
AER Pereira, MÂ Rodrigues, RD Novaes… - Experimental …, 2017 - Elsevier
We used a murine model of Schistosoma mansoni (SM) infection and lipopolysaccharide
(LPS)-induced endotoxicity to investigate if these conditions can interact to modify the …
(LPS)-induced endotoxicity to investigate if these conditions can interact to modify the …