Obesity and the obesity paradox in heart failure

TB Horwich, GC Fonarow, AL Clark - Progress in cardiovascular diseases, 2018 - Elsevier
Obesity continues to be a public health problem in the general population, and also
significantly increases the risk for the development of new-onset heart failure (HF). However …

Diuretic response in acute heart failure—pathophysiology, evaluation, and therapy

JM Ter Maaten, MAE Valente, K Damman… - Nature Reviews …, 2015 - nature.com
The administration of loop diuretics to achieve decongestion is the cornerstone of therapy for
acute heart failure. Unfortunately, impaired response to diuretics is common in these …

BNP-guided vs symptom-guided heart failure therapy: the Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME …

M Pfisterer, P Buser, H Rickli, M Gutmann, P Erne… - Jama, 2009 - jamanetwork.com
Context It is uncertain whether intensified heart failure therapy guided by N-terminal brain
natriuretic peptide (BNP) is superior to symptom-guided therapy. Objective To compare 18 …

Hyponatremia in acute decompensated heart failure: depletion versus dilution

FH Verbrugge, P Steels, L Grieten, P Nijst… - Journal of the American …, 2015 - jacc.org
Hyponatremia frequently poses a therapeutic challenge in acute decompensated heart
failure (ADHF). Treating physicians should differentiate between depletional versus …

Obesity and the obesity paradox in heart failure

AL Clark, GC Fonarow, TB Horwich - Progress in cardiovascular diseases, 2014 - Elsevier
Obesity is a growing public health problem in the general population, and significantly
increases the risk for the development of new-onset heart failure (HF). However, in the …

Acute decompensated heart failure and the cardiorenal syndrome

KV Liang, AW Williams, EL Greene… - Critical care …, 2008 - journals.lww.com
Heart failure is one of the leading causes of hospitalizations in the United States.
Concomitant and significant renal dysfunction is common in patients with heart failure …

Changes of natriuretic peptides predict hospital admissions in patients with chronic heart failure: a meta-analysis

G Savarese, F Musella, C D'Amore, E Vassallo… - JACC: heart failure, 2014 - jacc.org
Objectives: The goal of this study was to explore the association between changes in B-type
natriuretic peptide (BNP) and N-terminal pro–B-type natriuretic peptide (NT-proBNP) plasma …

The wrong white crystals: not salt but sugar as aetiological in hypertension and cardiometabolic disease

JJ DiNicolantonio, SC Lucan - Open heart, 2014 - openheart.bmj.com
Cardiovascular disease is the leading cause of premature mortality in the developed world,
and hypertension is its most important risk factor. Controlling hypertension is a major focus …

Dietary sodium intake in heart failure

D Gupta, VV Georgiopoulou, AP Kalogeropoulos… - Circulation, 2012 - Am Heart Assoc
Dietary sodium restriction is arguably the most frequent self-care behavior recommended to
patients with heart failure (HF) 1, 2 and is endorsed by all HF guidelines. 2–10 However, the …

Medium term effects of different dosage of diuretic, sodium, and fluid administration on neurohormonal and clinical outcome in patients with recently compensated …

S Paterna, G Parrinello, S Cannizzaro, S Fasullo… - The American journal of …, 2009 - Elsevier
Studies have shown that patients with compensated heart failure (HF) receiving high diuretic
doses associated with normal sodium diet and fluid intake restrictions demonstrated …