Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

Neisseria gonorrhoeae is evolving into a superbug with resistance to previously and
currently recommended antimicrobials for treatment of gonorrhea, which is a major public …

Recently, the first Neisseria gonorrhoeae strain (H041) highly resistant to the expanded-
spectrum cephalosporins (ESCs) ceftriaxone and cefixime, which are the last remaining …

Recently, the first Neisseria gonorrhoeae strain (H041) that is highly resistant to the
extended-spectrum cephalosporin (ESC) ceftriaxone, the last remaining option for empirical …

In the 1980s, Gram-negative pathogens appeared to have been beaten by oxyimino-
cephalosporins, carbapenems, and fluoroquinolones. Yet these pathogens have fought …

Neisseria gonorrhoeae has developed antimicrobial resistance (AMR) to all drugs
previously and currently recommended for empirical monotherapy of gonorrhoea. In vitro …

The new superbug Neisseria gonorrhoeae has retained resistance to antimicrobials
previously recommended for first-line treatment and has now demonstrated its capacity to …

The strict human pathogen Neisseria gonorrhoeae has caused gonorrhea for thousands of
years, and currently gonorrhea is the second most prevalent bacterial sexually transmitted …

The paper presents various issues related to the increasing drug resistance of Neisseria
gonorrhoeae and the occurrence and spread of multidrug-resistant clones. One of the most …

Importance Although cephalosporins are the cornerstone of treatment of Neisseria
gonorrhoeae infections, cefixime is the only oral antimicrobial option. Increased minimum …