[HTML][HTML] Chemotherapeutic effects of Apigenin in breast cancer: Preclinical evidence and molecular mechanisms; enhanced bioavailability by nanoparticles

M Adel, M Zahmatkeshan, A Akbarzadeh, N Rabiee… - Biotechnology …, 2022 - Elsevier
This review highlights using nanotechnology in increasing the bioavailability of AP
(Apigenin) to enhance its therapeutic efficacy in breast cancer treatment. Breast cancer is …

Specialized phenolic compounds in seeds: Structures, functions, and regulations

M Corso, F Perreau, G Mouille, L Lepiniec - Plant Science, 2020 - Elsevier
Plants produce a huge diversity of specialized metabolites (SM) throughout their life cycle
that play important physiological and ecological functions. SM can protect plants and seeds …

Metabolomics and Molecular Networking to Characterize the Chemical Space of Four Momordica Plant Species

AT Ramabulana, D Petras, NE Madala, F Tugizimana - Metabolites, 2021 - mdpi.com
Momordica plant species (Cucurbitaceae), have been used for centuries in traditional
medicine and for nutritional purposes. Plants from this family are thus claimed to be …

Expanding urinary metabolite annotation through integrated mass spectral similarity networking

FC Neto, D Raftery - Analytical chemistry, 2021 - ACS Publications
The urine metabolome constitutes a rich source of functional information reflecting
physiological states that are influenced by distinct conditions and biological stresses, such …

Rosemary (Rosmarinus officinalis L.) Glycolic Extract Protects Liver Mitochondria from Oxidative Damage and Prevents Acetaminophen-Induced Hepatotoxicity

NSS Guimarães, VS Ramos, LFL Prado-Souza… - Antioxidants, 2023 - mdpi.com
Rosmarinus officinalis L.(rosemary) is an aromatic culinary herb. Native to the
Mediterranean region, it is currently cultivated worldwide. In addition to its use as a …

[HTML][HTML] Metabolômica de plantas: métodos e desafios

AC Pilon, DM Selegato, RP Fernandes, PCP Bueno… - Química …, 2020 - SciELO Brasil
Metabolomics has played a central role in various areas of plant sciences, offering new
perspectives for the advancement of agriculture, drug discovery, chemical ecology and …

Nontarget Screening and Toxicity Evaluation of Diol Esters of Okadaic Acid and Dinophysistoxins Reveal Intraspecies Difference of Prorocentrum lima

H Wu, J Chen, J Peng, Y Zhong, G Zheng… - Environmental …, 2020 - ACS Publications
High-resolution mass spectrometry (HRMS) analysis with the assistance of molecular
networking was used to investigate intracellular toxin profiles of five Prorocentrum lima (P …

Application of feature-based molecular networking and MassQL for the MS/MS fragmentation study of depsipeptides

DM Selegato, AC Zanatta, AC Pilon… - Frontiers in Molecular …, 2023 - frontiersin.org
The Feature-based Molecular Networking (FBMN) is a well-known approach for mapping
and identifying structures and analogues. However, in the absence of prior knowledge about …

LC-MS/DIA-based strategy for comprehensive flavonoid profiling: an Ocotea spp. applicability case

MF Alves, A Katchborian-Neto, PCP Bueno… - RSC …, 2024 - pubs.rsc.org
We introduce a liquid chromatography–mass spectrometry with data-independent
acquisition (LC-MS/DIA)-based strategy, specifically tailored to achieve comprehensive and …

Targeted isolation of terpenoid indole alkaloids from Melodinus cochinchinensis (Lour.) Merr. using molecular networking and their biological activities

F Li, Y Wang, S He, A Khan, Q Xue, Q Cui, L Liu… - Industrial Crops and …, 2020 - Elsevier
Abstract Melodinus cochinchinensis (Lour.) Merr. has been used in Traditional Chinese
Medicine for the management of various ailments, yet its chemical constituents are rarely …