The Photosensitizer Temoporfin (mTHPC) – Chemical, Pre‐clinical and Clinical Developments in the Last Decade

A Wiehe, MO Senge - Photochemistry and Photobiology, 2023 - Wiley Online Library
This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …

mTHPC–A drug on its way from second to third generation photosensitizer?

MO Senge - Photodiagnosis and Photodynamic Therapy, 2012 - Elsevier
5, 10, 15, 20-Tetrakis (3-hydroxyphenyl) chlorin (mTHPC, Temoporfin) is a widely
investigated second generation photosensitizer. Its initial use in solution form (Foscan®) is …

Understanding oxygen-deficient La2CuO4-δperovskite activated peroxymonosulfate for bisphenol A degradation: The role of localized electron within oxygen vacancy

H Chen, Y Xu, K Zhu, H Zhang - Applied Catalysis B: Environmental, 2021 - Elsevier
An A 2 BO 4-type oxygen-deficient perovskite (La 2 CuO 4-δ, LCO), which owns a better low-
temperature reducibility, more abundant oxygen vacancies (OVs) and surface oxygen …

Soret band shape indicates mTHPC distribution between β-cyclodextrins and serum proteins

I Yakavets, I Yankovsky, L Bezdetnaya, V Zorin - Dyes and Pigments, 2017 - Elsevier
Fluorescence and absorbance characteristics of 5, 10, 15, 20-tetra (m-hydroxyphenyl)
chlorin (mTHPC) in several organic solutions and in complexes with various biological …

The Molecular Bases of the Interaction between a Saponin from the Roots of Gypsophila paniculata L. and Model Lipid Membranes

B Korchowiec, J Korchowiec, K Kwiecińska… - International Journal of …, 2022 - mdpi.com
In view of the possible medical applications of saponins, the molecular structure of a
GOTCAB saponin from the roots of Gypsophila paniculata L. was determined by NMR. The …

Amphiphilic chlorins and bacteriochlorins in micellar environments. Molecular design, de novo synthesis, and photophysical properties

K Aravindu, O Mass, P Vairaprakash, JW Springer… - Chemical …, 2013 - pubs.rsc.org
The incorporation of amphiphilic tetrapyrrole macrocycles in organized media is of great
value for a variety of fundamental photochemical studies, yet work to date has chiefly …

Congo Red as a supramolecular carrier system for doxorubicin: an approach to understanding the mechanism of action

K Kwiecińska, A Stachowicz-Kuśnierz… - International Journal of …, 2022 - mdpi.com
The uptake and distribution of doxorubicin in the MCF7 line of breast-cancer cells were
monitored by Raman measurements. It was demonstrated that bioavailability of doxorubicin …

Membrane Activity of Tetra-p-guanidinoethylcalix[4]arene as a Possible Reason for Its Antibacterial Properties

G Sautrey, M Orlof, B Korchowiec… - The Journal of …, 2011 - ACS Publications
Tetra-p-guanidinoethylcalix [4] arene trifluoroacetate salt (CX1) was synthesized recently as
an antibacterial agent. It showed to be active in vitro against various Gram-positive and …

[HTML][HTML] A way to introducing a hydrophilic bioactive agent into model lipid membranes. The role of cetyl palmitate in the interaction of curcumin with 1, 2-dioleoyl-sn …

M Girardon, B Korchowiec, J Korchowiec… - Journal of Molecular …, 2020 - Elsevier
The interfacial behavior of curcumin, a model anti-inflammatory drug was studied upon
interaction with cetyl palmitate and 1, 2-dioleoyl-sn-glycero-3-phosphatidylcholine. Cetyl …

Insights into Transfer of Supramolecular Doxorubicin/Congo Red Aggregates through Phospholipid Membranes

A Stachowicz-Kuśnierz, P Rychlik, J Korchowiec… - Molecules, 2024 - mdpi.com
Doxorubicin (DOX) is a commonly used chemotherapeutic drug, from the anthracycline
class, which is genotoxic to neoplastic cells via a DNA intercalation mechanism. It is effective …