[HTML][HTML] Long-term human spaceflight and inflammaging: Does it promote aging?

M Capri, M Conte, E Ciurca, C Pirazzini… - Ageing Research …, 2023 - Elsevier
Spaceflight and its associated stressors, such as microgravity, radiation exposure,
confinement, circadian derailment and disruptive workloads represent an unprecedented …

Changes in interstitial fluid flow, mass transport and the bone cell response in microgravity and normogravity

F Wei, K Flowerdew, M Kinzel, LE Perotti, J Asiatico… - Bone Research, 2022 - nature.com
In recent years, our scientific interest in spaceflight has grown exponentially and resulted in
a thriving area of research, with hundreds of astronauts spending months of their time in …

Current knowledge about the impact of microgravity on gene regulation

TJ Corydon, H Schulz, P Richter, SM Strauch… - Cells, 2023 - mdpi.com
Microgravity (µ g) has a massive impact on the health of space explorers. Microgravity
changes the proliferation, differentiation, and growth of cells. As crewed spaceflights into …

Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses

K Grigorev, TM Nelson, EG Overbey, N Houerbi… - Nature …, 2024 - nature.com
The advent of civilian spaceflight challenges scientists to precisely describe the effects of
spaceflight on human physiology, particularly at the molecular and cellular level. Newer …

Next generation of astronauts or ESA astronaut 2.0 concept and spotlight on immunity

P Jacob, C Oertlin, B Baselet, LS Westerberg… - npj …, 2023 - nature.com
Although we have sent humans into space for more than 50 years, crucial questions
regarding immune response in space conditions remain unanswered. There are many …

Physiological consequences of space flight, including abnormal bone metabolism, space radiation injury, and circadian clock dysregulation: Implications of melatonin …

J Hirayama, A Hattori, A Takahashi… - Journal of pineal …, 2023 - Wiley Online Library
Exposure to the space environment induces a number of pathophysiological outcomes in
astronauts, including bone demineralization, sleep disorders, circadian clock dysregulation …

The global cooperation in asteroid mining based on AHP, entropy and TOPSIS

R Fan, H Zhang, Y Gao - Applied Mathematics and Computation, 2023 - Elsevier
In this paper we introduce an equity evaluation index (EEI) to measure the global equity on
asteroid mining, and present a global equity evaluation model by applying the analytic …

Long-term spaceflight composite stress induces depression and cognitive impairment in astronauts—insights from neuroplasticity

Y Yin, J Liu, Q Fan, S Zhao, X Wu, J Wang, Y Liu… - Translational …, 2023 - nature.com
The environment on the space station is quite unique compared to Earth, which is a
composite of multiple stressors, such as microgravity, isolation, confinement, noise …

Physiological alterations in relation to space flight: the role of nutrition

S Chaloulakou, KA Poulia, D Karayiannis - Nutrients, 2022 - mdpi.com
Astronauts exhibit several pathophysiological changes due to a variety of stressors related
to the space environment, including microgravity, space radiation, isolation, and …

Investigating cardiorespiratory interaction using ballistocardiography and seismocardiography—a narrative review

P Balali, J Rabineau, A Hossein, C Tordeur, O Debeir… - Sensors, 2022 - mdpi.com
Ballistocardiography (BCG) and seismocardiography (SCG) are non-invasive techniques
used to record the micromovements induced by cardiovascular activity at the body's center …