Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

[HTML][HTML] Protective roles and protective mechanisms of neutralizing antibodies against SARS-CoV-2 infection and their potential clinical implications

EC Abebe, TA Dejenie - Frontiers in Immunology, 2023 - frontiersin.org
Neutralizing antibodies (NAbs) are central players in the humoral immunity that defends the
body from SARS-CoV-2 infection by blocking viral entry into host cells and neutralizing their …

Anti-spike protein assays to determine SARS-CoV-2 antibody levels: a head-to-head comparison of five quantitative assays

T Perkmann, N Perkmann-Nagele, T Koller… - Microbiology …, 2021 - Am Soc Microbiol
Reliable quantification of the antibody response to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is highly relevant, eg, for identifying possible vaccine failure …

Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers

EU Patel, EM Bloch, W Clarke, YH Hsieh… - Journal of Clinical …, 2021 - Am Soc Microbiol
Accurate serological assays to detect antibodies to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) are needed to characterize the epidemiology of SARS-CoV-2 …

[HTML][HTML] Analytical and clinical performances of five immunoassays for the detection of SARS-CoV-2 antibodies in comparison with neutralization activity

A Padoan, F Bonfante, M Pagliari, A Bortolami… - …, 2020 - thelancet.com
Background Reliable high-throughput serological assays for SARS-CoV-2 antibodies are
urgently needed for the effective containment of the COVID-19 pandemic, as it is of crucial …

Convalescent plasma with a high level of virus-specific antibody effectively neutralizes SARS-CoV-2 variants of concern

M Li, EJ Beck, O Laeyendecker, Y Eby… - Blood …, 2022 - ashpublications.org
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants severely limits available effective monoclonal antibody therapies. Effective drugs …

[HTML][HTML] T cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibodies and disease severity

R Elyanow, TM Snyder, SC Dalai, RM Gittelman… - JCI insight, 2022 - ncbi.nlm.nih.gov
BACKGROUND Measuring the immune response to SARS-CoV-2 enables assessment of
past infection and protective immunity. SARS-CoV-2 infection induces humoral and T cell …

[HTML][HTML] Evaluation of a commercial ELISA as alternative to plaque reduction neutralization test to detect neutralizing antibodies against SARS-CoV-2

N Hofmann, M Grossegesse, M Neumann… - Scientific Reports, 2022 - nature.com
High-throughput detection of neutralizing antibodies against SARS-CoV-2 presents a
valuable tool for vaccine trials or investigations of population immunity. We evaluate the …

[HTML][HTML] Serological response in lung transplant recipients after two doses of SARS-CoV-2 mRNA vaccines

M Narasimhan, L Mahimainathan, AE Clark, A Usmani… - Vaccines, 2021 - mdpi.com
Background: Lung-transplant (LT) recipients are at high risk for COVID-19 due to
immunosuppression and respiratory tropism of SARS-CoV-2. The information on the effect of …

Evaluation of high-throughput SARS-CoV-2 serological assays in a longitudinal cohort of patients with mild COVID-19: clinical sensitivity, specificity, and association …

A Bal, B Pozzetto, MA Trabaud, V Escuret… - Clinical …, 2021 - academic.oup.com
Background The association between SARS-CoV-2 commercial serological assays and
virus neutralization test (VNT) has been poorly explored in mild patients with COVID-19 …