[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

The liver as an endocrine organ—linking NAFLD and insulin resistance

MJ Watt, PM Miotto, W De Nardo… - Endocrine …, 2019 - academic.oup.com
The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …

Characterizing extracellular vesicles and their diverse RNA contents

EM Veziroglu, GI Mias - Frontiers in Genetics, 2020 - frontiersin.org
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Analysis and biomedical applications of functional cargo in extracellular vesicles

F Qian, Z Huang, H Zhong, Q Lei, Y Ai, Z Xie, T Zhang… - ACS …, 2022 - ACS Publications
Extracellular vesicles (EVs) can facilitate essential communication among cells in a range of
pathophysiological conditions including cancer metastasis and progression, immune …

Extracellular vesicle–and particle-mediated communication shapes innate and adaptive immune responses

FA Pelissier Vatter, M Cioffi, SJ Hanna… - Journal of Experimental …, 2021 - rupress.org
Intercellular communication among immune cells is vital for the coordination of proper
immune responses. Extracellular vesicles and particles (EVPs) act as messengers in …

A guide to mass spectrometric analysis of extracellular vesicle proteins for biomarker discovery

I Jalaludin, DM Lubman, J Kim - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …

[HTML][HTML] Metabolites as extracellular vesicle cargo in health, cancer, pleural effusion, and cardiovascular diseases: An emerging field of study to diagnostic and …

Y Zhang, F Liang, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Extracellular vesicles (EVs) are highly diverse nanoscale membrane-bound structures
released from different cell types into the extracellular environment. They play essential …

Metabolomics identifies serum and exosomes metabolite markers of pancreatic cancer

L Tao, J Zhou, C Yuan, L Zhang, D Li, D Si, D Xiu… - Metabolomics, 2019 - Springer
Introduction Pancreatic cancer (PC) is one of the most aggressive malignancies, and it's
difficult to diagnosis PC at an early stage, which leads to the poor prognosis of PC …

Recent developments along the analytical process for metabolomics workflows

C Gonzalez-Riano, D Dudzik, A Garcia… - Analytical …, 2019 - ACS Publications
We are in the midst of a shift in biological research paradigms from reductionist
methodologies that generate a hypothesis and rigorously and quantitatively measure the …