The bioactive peptide adrenomedullin (AM) exerts pleiotropic actions in various organs and
tissues. In the heart, AM has an inhibitory effect on ventricular remodeling, suppressing …

Adrenomedullin (AM) is a regulatory peptide whose involvement in tumour progression is
becoming more relevant with recent studies. AM is produced and secreted by the tumour …

Angiogenesis, the fundamental process by which new blood vessels form from existing
ones, depends on precise spatial and temporal gene expression within specific …

Most of current gene expression signatures for cancer prognosis are based on risk scores,
usually calculated as some summaries of expression levels of the signature genes, whose …

Simple Summary Neurokinins A and B, adrenomedullin, adrenomedullin 2, amylin, and
calcitonin gene-related peptide are essential in different tumors. These peptides are …

Cuproptosis, a new type of copper‐induced cell death, is involved in the antitumor activity
and resistance of multiple chemotherapeutic drugs. Our previous study revealed that …

The poor prognosis of clear-cell renal cell carcinoma (ccRCC) patients is due to progression
and targeted drug resistance, but the underlying molecular mechanisms need further …

Calcitonin receptor-like (CALCRL) is a G-protein-coupled neuropeptide receptor involved in
the regulation of blood pressure, angiogenesis, cell proliferation, and apoptosis, and is …

Platelet-activating factor receptor (PAFR), a G-protein–coupled receptor, has been
implicated in tumorigenesis, but its contributions to metastatic progression have not been …

The classic model of tumor suppression implies that malignant transformation requires full
“two-hit” inactivation of a tumor-suppressor gene. However, more recent work in mice has …