Disclosed are methods of preventing or treating cardiac arrhythmia. In one embodiment, the
methods include admin istering to an amount of at least one polynucleotide that modulates …

Disclosed are methods and systems for modulating electrical behavior of cardiac cells.
Preferred methods include administering a polynucleotide or cell-based composition that …

Disclosed is an invention for focally modulating the activity of a calcium channel in a
mammal. In one aspect, the invention features a method that includes contacting a pre …

WO2013020235A1 - Methods and compositions for modulating voltage-gated calcium channel
function - Google Patents WO2013020235A1 - Methods and compositions for modulating …

Provided are antibodies, and antigen-binding fragments thereof, which specifically bind to
an extracellular poor loop of an alpha 1a subunit of L-type voltage gated calcium channel …

Disclosed is an invention for focally modulating the activity of a calcium channel in a
mammal. In one aspect, the invention features a method that includes contacting a pre …

As an alternative strategy to electronic pacemaker devices, we explored the feasibility of
converting normally-quiescent ventricular myocytes into pacemakers by somatic cell fusion …

Disclosed are methods of preventing or treating cardiac arrhythmia. In one embodiment, the
methods include administering to an amount of at least one polynucleotide that modulates …

Knock-down of L-type calcium channel beta subunit (LTCCβ) attenuates the hypertrophic
response both in vitro and in vivo without compromising systolic performance. Knock-down …

Knock-down of L-type calcium channel beta subunit (LTCCβ) attenuates the hypertrophic
response both in vitro and in vivo without compromising systolic performance. Knock-down …