Purpose Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors
comprising various breast cancers simply defined by the absence of estrogen receptor …

Many factors must be considered and discussed with women when initiating a contraceptive
method and the risk of venous thromboembolism (VTE) is one of them. In this review, we …

The role of the androgen receptor (AR) in estrogen receptor (ER)-α-positive breast cancer is
controversial, constraining implementation of AR-directed therapies. Using a diverse …

Triple negative breast cancer (TNBC) is a subtype of breast tumor lacking hormone
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …

Triple-negative breast cancer (TNBC) accounts for 15% to 20% of breast cancer cases and
is characterized by the absence of estrogen, progesterone, and human epidermal growth …

Androgens and estrogens are known to be critical regulators of mammalian physiology and
development. While these two classes of steroids share similar structures (in general …

Breast cancer (BC) is a hormone-related tumor. Despite the progress in BC therapy, this
disease still remains the most common cancer amongst women around the world. This is …

Despite significant progress in breast cancer (BC) therapy, it is globally the most commonly
diagnosed cancer and leads to the death of over 650,000 women annually. Androgen …

Introduction The androgen receptor (AR) is widely expressed in breast cancers and has
been proposed as a therapeutic target in estrogen receptor alpha (ER) negative breast …

Abstract The Androgen Receptor (AR), a member of the steroid hormone receptor family,
plays important roles in the physiology and pathology of diverse tissues. AR ligands, which …