First-and second-generation sequencing technologies have led the way in revolutionizing
the field of genomics and beyond, motivating an astonishing number of scientific advances …

The emergence of next-generation sequencing platforms led to resurgence of research in
whole-genome shotgun assembly algorithms and software. DNA sequencing data from the …

The evolution in next-generation sequencing (NGS) technology has led to the development
of many different assembly algorithms, but few of them focus on assembling the organelle …

Next-generation massively parallel DNA sequencing technologies provide ultrahigh
throughput at a substantially lower unit data cost; however, the data are very short read …

Widespread adoption of massively parallel deoxyribonucleic acid (DNA) sequencing
instruments has prompted the recent development of de novo short read assembly …

DNA sequence represents a single format onto which a broad range of biological
phenomena can be projected for high-throughput data collection. Over the past three years …

We have developed a new set of algorithms, collectively called “Velvet,” to manipulate de
Bruijn graphs for genomic sequence assembly. A de Bruijn graph is a compact …

Advances in sequencing technologies and increased access to sequencing services have
led to renewed interest in sequence and genome assembly. Concurrently, new applications …

Using next-generation sequencing technologies it is possible to resequence entire plant
genomes or sample entire transcriptomes more efficiently and economically and in greater …

Background: For the past 30 years, the Sanger method has been the dominant approach
and gold standard for DNA sequencing. The commercial launch of the first massively …