Human papillomavirus in the setting of immunodeficiency: Pathogenesis and the emergence of next-generation therapies to reduce the high associated cancer risk

RV Hewavisenti, J Arena, CL Ahlenstiel… - Frontiers in …, 2023 - frontiersin.org
Human papillomavirus (HPV), a common sexually transmitted virus infecting mucosal or
cutaneous stratified epithelia, is implicated in the rising of associated cancers worldwide …

The effect of chronic kidney disease on T cell alloimmunity

PD Winterberg, ML Ford - Current opinion in organ transplantation, 2017 - journals.lww.com
The mechanisms by which CKD alters the differentiation and activation status of T-cell
subsets is poorly understood. Further research is also needed to understand which cell …

CD4+ T cell lymphopenia predicts mortality from Pneumocystis pneumonia in kidney transplant patients

T Freiwald, S Büttner, NT Cheru… - Clinical …, 2020 - Wiley Online Library
Abstract Background Pneumocystis jirovecii pneumonia (PcP) remains a life‐threatening
opportunistic infection after solid organ transplantation, even in the era of Pneumocystis …

Time-dependent lymphocyte count after transplantation is associated with higher risk of graft failure and death

A Dujardin, M Lorent, Y Foucher, C Legendre… - Kidney international, 2021 - Elsevier
The transplantation field requires the identification of specific risk factors associated with the
level of immunosuppression. Here, our aim was to analyze the association between the …

Pre-transplant thymic function predicts is associated with patient death after kidney transplantation

C Courivaud, J Bamoulid, T Crepin, E Gaiffe… - Frontiers in …, 2020 - frontiersin.org
Accelerated thymic involution is a main feature of end-stage renal disease (ESRD)-
associated immune senescence. Recent evidences suggest that ESRD-associated immune …

[HTML][HTML] Kidney Transplantation and Cellular Immunity Dynamics: Immune Cell Alterations and Association with Clinical and Laboratory Parameters

L Vagiotas, G Lioulios, M Panteli, K Ouranos… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: The purpose of this study was to evaluate numerical changes in
immune cells after successful kidney transplantation and associate their recovery with …

Solid Organ Transplantation Is Associated with an Increased Rate of Mismatch Repair Deficiency and PIK3CA Mutations in Colorectal Cancer

ES Christenson, V Lee, H Wang, M Yarchoan… - Current …, 2022 - mdpi.com
Solid organ transplants are associated with a modestly increased risk of colorectal cancers
(CRC). However, the molecular profile of these cancers has not been described. We …

Leukopenia in autosomal dominant polycystic kidney disease: a single-center cohort of kidney transplant candidates with post-transplantation follow-up

P Schellekens, E Van Loon, M Coemans… - Clinical Kidney …, 2023 - academic.oup.com
Background Autosomal dominant polycystic kidney disease (ADPKD) has occasionally been
associated with lower peripheral white blood cell (WBC) counts. This study aimed to …

[HTML][HTML] Uremia-associated premature aging of T cells does not predict infectious complications after renal transplantation

B Dedeoglu, RWJ Meijers, M Klepper… - American Journal of …, 2016 - Elsevier
Patients with end-stage renal disease have prematurely aged T cell systems. We tested
whether T cell aging parameters were associated with the risk of infections after renal …

Antithymocyte globulins in renal transplantation—from lymphocyte depletion to lymphocyte activation: the doubled-edged sword

J Bamoulid, T Crépin, C Courivaud, JM Rebibou… - Transplantation …, 2017 - Elsevier
Compelling data suggest that lymphocyte depletion following T cell depleting therapy may
induce prolonged CD4 T cell lymphopenia and trigger lymphocyte activation in some …